Growth Factors & Cytokines

Recombinant Human IL-7

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Product Details

Catalogue Number: 200-07
Description:
Recombinant Human IL-7

IL-7 is a hematopoietic growth factor that primarily affects early B and T cells.  Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2.  Human and murine IL-7 are cross-species reactive.  Recombinant Human IL-7 is a 17.5 kDa protein containing 153 amino acid residues.

Source: E.coli

AA Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH

Synonyms: Interleukin-7, Lymphopoietin 1(LP-1), pre-B cell factor

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.

This product has been tested against the WHO standard. International Unit information can be found here.

Calculated Molecular Weight: 17.5 kDa

Accession Number: P13232

Gene ID: 3574

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Wang, W
Title
Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors.
Citation
Advanced science (Weinheim, Baden-Wurttemberg, Germany); 9(22) pge2105810
PubMed Id
First Author
Loef, E J
Title
Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses.
Citation
The Journal of Biological Chemistry; 298(7) pg102112
PubMed Id
First Author
Moosmann, C
Title
Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair.
Citation
STAR Protocols; 3(1) pg101031
PubMed Id