Chemokines

Recombinant Human IL-8 (CXCL8) (72 a.a.)

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Product Details

Catalogue Number: 200-08M
Description:

IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues.

Source: E.coli

Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1

AA Sequence: SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 8.4 kDa

Accession Number: P10145

Gene ID: 3576

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

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Dietachmayr, M
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Nature Communications; 11(1) pg1268
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Frommhold, D
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Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation.
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