Animal-Free Recombinant Human KGF (FGF-7) 1 ReviewsSubmit a Review Product Details Catalog Number: AF-100-19 Description: KGF (FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF-7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF (FGF-7) signals through FGFR 2b. KGF (FGF-7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Human KGF (FGF-7) is an 18.9 kDa protein consisting of 163 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7 AA Sequence: CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.1-15 ng/ml. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 18.9 kDa Accession Number: P21781 Gene ID: 2252 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) Cross Reactivity Cited in References: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular FGF Superfamily Immune System Stem Cells & Differentiation Wound Healing Diabetes/Weight Regulation Recent Citations First Author Hogrebe, N J Title Generation of insulin-producing pancreatic β cells from multiple human stem cell lines Citation Nature Protocols; 16(9) pg4109-4143 PubMed ID 34349281 First Author Rezanejad, H Title Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic. Citation Stem Cell Reports; 10(3) pg725-738 PubMed ID 29478894 First Author Maitra, M Title Mutant surfactant A2 proteins associated with familial pulmonary fibrosis and lung cancer induce TGF-β1 secretion. Citation Proceedings of the National Academy of Sciences of the United States of America; 109(51) pg21064-9 PubMed ID 23223528 Product Reviews Existing reviews Good product This product worked well for my project. The price is reasonable and lower than most of vendors. From: Jin | Date: 8/26/2020 × Good product This product worked well for my project. The price is reasonable and lower than most of vendors. From: Jin | Date: 8/26/2020 Close
