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Growth Factors & Cytokines

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Recombinant Human KGF (FGF-7)

Product Details

Catalog Number: 100-19
Description:

KGF (FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF-7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF (FGF-7) signals through FGFR 2b. KGF (FGF-7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Human KGF (FGF-7) is an 18.9 kDa protein consisting of 163 amino acid residues.

Source: E.coli

Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7

AA Sequence: CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.1-15 ng/ml.

Calculated Molecular Weight: 18.9 kDa

Accession Number: P21781

Gene ID: 2252

Cross Reactivity Cited in References:
Human, Leech, Mouse, Rat
Research Interest
Angiogenesis/Cardiovascular FGF Superfamily Immune System Stem Cells & Differentiation Wound Healing
References References
PubMed PubMed
SDS SDS
Product Line Product Line

Country Of Origin: USA

Not for human use.

Product Reviews

Existing reviews
It works well
It works well both in human and mouse organoid culture.
From:  Eun Joo | Date:  7/8/2020
Excellent quality
We utilize FGF7 as part of lung cancer organoid media for cancers which do not have EGFR mutations. We have had great results and excellent service.
From:  Dora | Date:  7/24/2020