Recombinant Human KGF (FGF-7) 3 ReviewsSubmit a Review Product Details Catalogue Number: 100-19 Description: KGF (FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF-7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF (FGF-7) signals through FGFR 2b. KGF (FGF-7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Human KGF (FGF-7) is an 18.9 kDa protein consisting of 163 amino acid residues. Source: E.coli Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7 AA Sequence: CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.1-15 ng/ml. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 18.9 kDa Accession Number: P21781 Gene ID: 2252 crossreactivity: Human, Leech, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular FGF Superfamily Immune System Stem Cells & Differentiation Wound Healing Diabetes/Weight Regulation product.subtitle.recentcitations First Author Busslinger, G A Title Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution. Citation Cell Reports; 34(10) pg108819 PubMed Id 33691112 First Author Zhang, X Title Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. Citation The Journal of Biological Chemistry; 281(23) pg15694-700 PubMed Id 16597617 First Author Yang, J Title GATA6-AS1 Regulates GATA6 Expression to Modulate Human Endoderm Differentiation. Citation Stem Cell Reports; 15(3) pg694-705 PubMed Id 32795420 product.subtitle.productreviews Existing reviews It works well It works well both in human and mouse organoid culture. From: Eun Joo | Date: 7/8/2020 × It works well It works well both in human and mouse organoid culture. From: Eun Joo | Date: 7/8/2020 Close Excellent quality We utilize FGF7 as part of lung cancer organoid media for cancers which do not have EGFR mutations. We have had great results and excellent service. From: Dora | Date: 7/24/2020 × Excellent quality We utilize FGF7 as part of lung cancer organoid media for cancers which do not have EGFR mutations. We have had great results and excellent service. From: Dora | Date: 7/24/2020 Close Great for organoids! We use this in two types patient tumor organoid media and have wonderful results in each. From: Julie-Ann | Date: 8/3/2021 × Great for organoids! We use this in two types patient tumor organoid media and have wonderful results in each. From: Julie-Ann | Date: 8/3/2021 Close
