Recombinant Human MCP-4 (CCL13) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-24 Description: The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-4 is an 8.6 kDa protein containing 75 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Source: E.coli Synonyms: Monocyte Chemotactic Protein-4, CCL13, NCC-1 AA Sequence: QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration of 10.0-100.0 ng/ml. Calculated Molecular Weight: 8.6 kDa Accession Number: Q99616 crossreactivity: Bacteria, Human, Human + Mouse, Monkey, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Cancer Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy product.subtitle.recentcitations First Author Tiffany, H L Title Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309. Citation The Journal of Experimental Medicine; 186(1) pg165-70 PubMed Id 9207005 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871 First Author Sabroe, I Title A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry. Citation The Journal of Biological Chemistry; 275(34) pg25985-92 PubMed Id 10854442
