Recombinant Human MIP-3 (CCL23) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-29 Description: MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes, and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant Human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Macrophage Inflammatory Protein-3, CCL23, MPIF-1, Ck-β8 AA Sequence: RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human T cell population using a concentration of 10-50 ng/ml. Calculated Molecular Weight: 11.3 kDa Accession Number: P55773 Gene ID: 6368 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Mouse, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Krishnan, V Title Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1 Citation Communications Biology; 3(1) pg524 PubMed Id 32963283 First Author Lee, A W Title A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citation The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed Id 31167786 First Author Binti Mohd Amir, N A Title Evidence for the Existence of a CXCL17 Receptor Distinct from GPR35. Citation Journal of immunology (Baltimore, Md. : 1950); 201(2) pg714-724 PubMed Id 29875152
