Recombinant Human PlGF-3 0 ReviewsSubmit a Review Product Details Catalogue Number: 100-57 Description: PlGF-3 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-3 is expressed exclusively in the placenta. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. PlGF-3 lacks heparin binding affinity. Recombinant Human PlGF-3 is a 45.7 kDa disulfide-linked homodimeric protein of two 203 amino acid polypeptide chains. Source: E.coli Synonyms: Placenta Growth Factor-3, PGFL AA Sequence (monomer): LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRHSPGRQS PDMPGDFRAD APSFLPPRRS LPMLFRMEWG CALTGSQSAV WPSSPVPEEI PRMHPGRNGK KQQRKPLREK MKPERCGDAV PRR Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-50.0 ng/ml. Calculated Molecular Weight: 45.7 kDa Accession Number: P49763 Gene ID: 5228 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Immune System Inflammation Stem Cells & Differentiation product.subtitle.recentcitations First Author Martino, M M Title Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix. Citation Proceedings of the National Academy of Sciences of the United States of America; 110(12) pg4563-8 PubMed Id 23487783
