Recombinant Murine BCA-1/BLC (CXCL13) 0 ReviewsSubmit a Review Product Details Catalog Number: 250-24 Description: BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor, CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes, and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Murine BLC is a 9.8 kDa protein containing 88 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines. Source: E.coli Synonyms: B cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand AA Sequence: ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human B cells. Calculated Molecular Weight: 9.8 kDa Accession Number: O55038 Gene ID: 55985 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Mouse, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing Recent Citations First Author Ma, L Title ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons. Citation The Journal of Experimental Medicine; 218(12) PubMed ID 34762123 First Author Cruz-Zárate, D Title Myo1g is required for efficient adhesion and migration of activated B lymphocytes to inguinal lymph nodes Citation Scientific Reports; 11(1) pg7197 PubMed ID 33785780 First Author Shi, J Title PD-1 Controls Follicular T Helper Cell Positioning and Function. Citation Immunity; 49(2) pg264-274.e4 PubMed ID 30076099
