Recombinant Murine FGF-10 0 ReviewsSubmit a Review Product Details Catalog Number: 450-61 Description: FGF-10 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-10 is most related to KGF/FGF-7, and is expressed during the development and, preferentially, in adult lungs. It signals through FGFR 2b. Recombinant Murine FGF-10 is a 17.0 kDa protein consisting of 148 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor‐10, FGFA, Keratinocyte Growth Factor‐2 AA Sequence: SSAGRHVRSY NHLQGDVRWR RLFSFTKYFL TIEKNGKVSG TKNEDCPYSV LEITSVEIGV VAVKAINSNY YLAMNKKGKL YGSKEFNNDC KLKERIEENG YNTYASFNWQ HNGRQMYVAL NGKGAPRRGQ KTRRKNTSAH FLPMTIQT Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8). Calculated Molecular Weight: 17 kDa Accession Number: O35565 Gene ID: 14165 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Wound Healing Recent Citations First Author Ford, M J Title Oviduct epithelial cells constitute two developmentally distinct lineages that are spatially separated along the distal-proximal axis. Citation Cell Reports; 36(10) pg109677 PubMed ID 34496237 First Author Wojnarowicz, P M Title Anti-tumor effects of an ID antagonist with no observed acquired resistance. Citation NPJ Breast Cancer; 7(1) pg58 PubMed ID 34031428 First Author Nikolaev, M Title Homeostatic mini-intestines through scaffold-guided organoid morphogenesis. Citation Nature; 585(7826) pg574-578 PubMed ID 32939089
