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Growth Factors & Cytokines

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Recombinant Murine IL-2

Product Details

Catalog Number: 212-12
Description:

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.  IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response.  IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.  Recombinant Murine IL-2 is a 17.2 kDa protein containing 148 amino acid residues.

Source: E.coli

Synonyms: T-cell growth factor (TCGF), Aldesleukin

AA Sequence: PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.

Calculated Molecular Weight: 17.2 kDa

Accession Number: P04351

Gene ID: 16183

Cross Reactivity Cited in References:
Human, Human + Mouse, Mouse,
Research Interest
CAR T Cell COVID-19 AIDS/HIV Cancer Cell Culture Diabetes/Weight Regulation Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Allergy Transplantation
References References
PubMed PubMed
SDS SDS
Product Line Product Line

Country Of Origin: USA

Not for human use.

Product Reviews

Existing reviews
Product with great consistency
We have been using this cytokine for splenic T cells in numerous publications for the past 10 years. Great consistency!
From:  Jin | Date:  7/21/2020
Reliable product
Our lab has been using Peprotech cytokines for many years because of its quality and reliability. Would highly recommend for assays in which murine T cells, splenocytes, or T cell clones need to be grown and stimulated.
From:  Diane | Date:  8/26/2020
For in vitro NKs expansion
We used this product for in vitro NKs expansion
From:  Aitziber | Date:  8/26/2020
Great consistent mouse recombinant IL-2
We have been using this recombinant mouse IL-2 for almost 20 years now in the lab. Our T cell cultures grow and expand very well with IL-2.
From:  Chirag | Date:  8/31/2020