Recombinant Murine IL-2

Product Details

Catalog Number: 212-12

Description:

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Murine IL-2 is a 17.2 kDa protein containing 148 amino acid residues.

Source: E.coli

Synonyms: T-cell growth factor (TCGF), Aldesleukin

AA Sequence: PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁶ units/mg.

Cross Reactivity:

Human , Human + Mouse, Mouse, N/A

Research Interest

Stem Cells & Differentiation

Diabetes/Weight Regulation

Country Of Origin: USA

Not for human use.

First Author

Title

Citation

Pubmed

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Proceedings of the National Academy of Sciences of the United States of America; 105(27) pg9337-42

8 Jul 2008

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Cell type-specific regulation of ITAM-mediated NF-kappaB activation by the adaptors, CARMA1 and CARD9.

Journal of immunology (Baltimore, Md. : 1950); 181(2) pg918-30

15 Jul 2008

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IL-15 serves as a costimulator in determining the activity of autoreactive CD8 T cells in an experimental mouse model of graft-versus-host-like disease.

Journal of immunology (Baltimore, Md. : 1950); 181(2) pg1109-19

15 Jul 2008

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LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

Cell; 134(1) pg97-111

11 Jul 2008

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Kindler, T

K-RasG12D-induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to gamma-secretase inhibitors.

Blood; 112(8) pg3373-82

15 Oct 2008

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The IL-10 and IFN-gamma pathways are essential to the potent immunosuppressive activity of cultured CD8+ NKT-like cells.

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Blood; 112(8) pg3283-92

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15 Aug 2008

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CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner.

The Journal of Experimental Medicine; 205(9) pg1975-81

1 Sep 2008

18710931
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IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development.

Journal of immunology (Baltimore, Md. : 1950); 181(5) pg3285-90

1 Sep 2008

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The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease.

The Journal of Experimental Medicine; 205(9) pg2005-17

1 Sep 2008

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Tonkin, D R

Regulatory T cells prevent transfer of type 1 diabetes in NOD mice only when their antigen is present in vivo.

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1 Oct 2008

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Journal of immunology (Baltimore, Md. : 1950); 181(7) pg4570-9

1 Oct 2008

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Kamimura, D

Endoplasmic reticulum stress regulator XBP-1 contributes to effector CD8+ T cell differentiation during acute infection.

Journal of immunology (Baltimore, Md. : 1950); 181(8) pg5433-41

15 Oct 2008

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Journal of immunology (Baltimore, Md. : 1950); 181(8) pg5462-72

15 Oct 2008

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A single CD8+ T cell epitope sets the long-term latent load of a murid herpesvirus.

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CXCL10 blockade protects mice from cyclophosphamide-induced cystitis.

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28 Oct 2008

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Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation.

The Journal of Biological Chemistry; 283(52) pg36344-53

26 Dec 2008

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PLoS Biology; 6(11) pge276

11 Nov 2008

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Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.

Journal of immunology (Baltimore, Md. : 1950); 181(11) pg7660-9

1 Dec 2008

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Regulated movement of CD4 in and out of the immunological synapse.

Journal of immunology (Baltimore, Md. : 1950); 181(12) pg8248-57

15 Dec 2008

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The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naÃ¯ve T cells.

Proceedings of the National Academy of Sciences of the United States of America; 105(51) pg20321-6

23 Dec 2008

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Molecular and Cellular Biology; 29(5) pg1222-34

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Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22.

The Journal of Experimental Medicine; 206(1) pg35-41

16 Jan 2009

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Journal of immunology (Baltimore, Md. : 1950); 182(2) pg948-56

15 Jan 2009

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Mucosally delivered Salmonella typhi expressing the Yersinia pestis F1 antigen elicits mucosal and systemic immunity early in life and primes the neonatal immune system for a vigorous anamnestic response to parenteral F1 boost.

Journal of immunology (Baltimore, Md. : 1950); 182(2) pg1211-22

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The Journal of Experimental Medicine; 206(1) pg89-97

16 Jan 2009

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Heat shock protein 70, released from heat-stressed tumor cells, initiates antitumor immunity by inducing tumor cell chemokine production and activating dendritic cells via TLR4 pathway.

Journal of immunology (Baltimore, Md. : 1950); 182(3) pg1449-59

1 Feb 2009

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20 Feb 2009

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Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge.

Journal of immunology (Baltimore, Md. : 1950); 182(6) pg3469-81

15 Mar 2009

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Journal of immunology (Baltimore, Md. : 1950); 182(6) pg3597-608

15 Mar 2009

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In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression.

The Journal of Experimental Medicine; 206(4) pg751-60

13 Apr 2009

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Statins impair CD1d-mediated antigen presentation through the inhibition of prenylation.

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15 Apr 2009

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13 Apr 2009

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Proceedings of the National Academy of Sciences of the United States of America; 106(17) pg7119-24

28 Apr 2009

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Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts.

Journal of immunology (Baltimore, Md. : 1950); 182(12) pg7527-38

15 Jun 2009

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Journal of immunology (Baltimore, Md. : 1950); 182(12) pg7698-707

15 Jun 2009

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Endotoxin augmented antigen-induced Th1 cell trafficking amplifies airway neutrophilic inflammation.

Journal of immunology (Baltimore, Md. : 1950); 182(12) pg7946-56

15 Jun 2009

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IL-2 regulates CD103 expression on CD4+ T cells in Scurfy mice that display both CD103-dependent and independent inflammation.

Journal of immunology (Baltimore, Md. : 1950); 183(2) pg1065-73

15 Jul 2009

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Journal of immunology (Baltimore, Md. : 1950); 183(3) pg1685-94

1 Aug 2009

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JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice.

Journal of immunology (Baltimore, Md. : 1950); 183(3) pg2183-92

1 Aug 2009

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An aberrant prostate antigen-specific immune response causes prostatitis in mice and is associated with chronic prostatitis in humans.

The Journal of Clinical Investigation; 119(7) pg2031-41

0 Jul 2009

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Semitekolou, M

Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease.

The Journal of Experimental Medicine; 206(8) pg1769-85

3 Aug 2009

19620629
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Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.

Nature Medicine; 15(8) pg930-9

0 Aug 2009

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Functional modulation of dendritic cells and macrophages by Japanese encephalitis virus through MyD88 adaptor molecule-dependent and -independent pathways.

Journal of immunology (Baltimore, Md. : 1950); 183(4) pg2462-74

15 Aug 2009

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Self-peptides prolong survival in murine autoimmunity via reduced IL-2/IL-7-mediated STAT5 signaling, CD8 coreceptor, and V alpha 2 down-regulation.

Journal of immunology (Baltimore, Md. : 1950); 183(5) pg3130-8

1 Sep 2009

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The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo.

Journal of immunology (Baltimore, Md. : 1950); 183(6) pg3751-60

15 Sep 2009

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T cell receptor sharing by cytotoxic T lymphocytes facilitates efficient virus control.

Proceedings of the National Academy of Sciences of the United States of America; 106(35) pg14984-9

1 Sep 2009

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Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines.

The Journal of Experimental Medicine; 206(10) pg2131-9

28 Sep 2009

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A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome.

Proceedings of the National Academy of Sciences of the United States of America; 106(40) pg17123-8

6 Oct 2009

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CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes.

Proceedings of the National Academy of Sciences of the United States of America; 106(42) pg17892-7

20 Oct 2009

19815530
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Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent.

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16 Oct 2009

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17 Nov 2009

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SOCS3 in T and NKT cells negatively regulates cytokine production and ameliorates ConA-induced hepatitis.

Journal of immunology (Baltimore, Md. : 1950); 183(11) pg7047-53

1 Dec 2009

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SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950); 183(11) pg7259-67

1 Dec 2009

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Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950); 183(11) pg7539-46

1 Dec 2009

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The Runx3 transcription factor augments Th1 and down-modulates Th2 phenotypes by interacting with and attenuating GATA3.

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15 Dec 2009

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Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model.

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23 Nov 2009

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Journal of immunology (Baltimore, Md. : 1950); 184(2) pg598-606

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c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells.

The Journal of Experimental Medicine; 206(13) pg3001-14

21 Dec 2009

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Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.

Blood; 115(13) pg2601-9

1 Apr 2010

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A reprogrammable mouse strain from gene-targeted embryonic stem cells.

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Hypochlorous acid: a natural adjuvant that facilitates antigen processing, cross-priming, and the induction of adaptive immunity.

Journal of immunology (Baltimore, Md. : 1950); 184(2) pg824-35

15 Jan 2010

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Proceedings of the National Academy of Sciences of the United States of America; 107(6) pg2556-61

9 Feb 2010

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FoxP3+RORgammat+ T helper intermediates display suppressive function against autoimmune diabetes.

Journal of immunology (Baltimore, Md. : 1950); 184(7) pg3377-85

1 Apr 2010

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Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease.

Journal of immunology (Baltimore, Md. : 1950); 184(8) pg4460-9

15 Apr 2010

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A new fractionation assay, based on the size of formaldehyde-crosslinked, mildly sheared chromatin, delineates the chromatin structure at promoter regions.

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IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors.

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29 Apr 2010

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Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells.

The Journal of Biological Chemistry; 285(29) pg22426-36

16 Jul 2010

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Identification of an NK/T cell-restricted progenitor in adult bone marrow contributing to bone marrow- and thymic-dependent NK cells.

Blood; 116(2) pg183-92

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Lnk constrains myeloproliferative diseases in mice.

The Journal of Clinical Investigation; 120(6) pg2058-69

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Elucidation of the integrin LFA-1-mediated signaling pathway of actin polarization in natural killer cells.

Blood; 116(8) pg1272-9

26 Aug 2010

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Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

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28 May 2010

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"Default" generation of neonatal regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 185(1) pg71-8

1 Jul 2010

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Definition of key variables for the induction of optimal NY-ESO-1-specific T cells in HLA transgene mice.

Journal of immunology (Baltimore, Md. : 1950); 185(6) pg3445-55

15 Sep 2010

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CD11c depletion severely disrupts Th2 induction and development in vivo.

The Journal of Experimental Medicine; 207(10) pg2089-96

27 Sep 2010

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Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction.

Journal of immunology (Baltimore, Md. : 1950); 185(7) pg4042-52

1 Oct 2010

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Control of the specificity of T cell-mediated anti-idiotype immunity by natural regulatory T cells.

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IL-2 mediates CD4+ T cell help in the breakdown of memory-like CD8+ T cell tolerance under lymphopenic conditions.

PLoS ONE; 5(9) pge12659

10 Sep 2010

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Takeuchi, H

Efficient induction of CCR9 on T cells requires coactivation of retinoic acid receptors and retinoid X receptors (RXRs): exaggerated T Cell homing to the intestine by RXR activation with organotins.

Journal of immunology (Baltimore, Md. : 1950); 185(9) pg5289-99

1 Nov 2010

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Differential suppression of tumor-specific CD8+ T cells by regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 185(9) pg5048-55

1 Nov 2010

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Dystrophin conferral using human endothelium expressing HLA-E in the non-immunosuppressive murine model of Duchenne muscular dystrophy.

Human Molecular Genetics; 20(2) pg235-44

15 Jan 2011

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TNF receptor-associated factor 3 is required for T cell-mediated immunity and TCR/CD28 signaling.

Journal of immunology (Baltimore, Md. : 1950); 186(1) pg143-55

1 Jan 2011

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RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling.

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12 Nov 2010

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SMAD3 prevents graft-versus-host disease by restraining Th1 differentiation and granulocyte-mediated tissue damage.

Blood; 117(5) pg1734-44

3 Feb 2011

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Allogeneic effector/memory Th-1 cells impair FoxP3+ regulatory T lymphocytes and synergize with chaperone-rich cell lysate vaccine to treat leukemia.

Blood; 117(5) pg1555-64

3 Feb 2011

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Retinoic acid-induced CCR9 expression requires transient TCR stimulation and cooperativity between NFATc2 and the retinoic acid receptor/retinoid X receptor complex.

Journal of immunology (Baltimore, Md. : 1950); 186(2) pg733-44

15 Jan 2011

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Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.

The Journal of Biological Chemistry; 286(7) pg5921-33

18 Feb 2011

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Antigen-Experienced CD4lo T Cells Are Linked to Deficient Contraction of the Immune Response in Autoimmune Diabetes.

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29 Sep 2010

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Apoptosis of purified CD4+ T cell subsets is dominated by cytokine deprivation and absence of other cells in new onset diabetic NOD mice.

PLoS ONE; 5(12) pge15684

31 Dec 2010

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Chemokine-containing exosomes are released from heat-stressed tumor cells via lipid raft-dependent pathway and act as efficient tumor vaccine.

Journal of immunology (Baltimore, Md. : 1950); 186(4) pg2219-28

15 Feb 2011

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Cyp26b1 regulates retinoic acid-dependent signals in T cells and its expression is inhibited by transforming growth factor-Î².

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7 Jan 2011

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The Journal of Biological Chemistry; 286(13) pg11110-8

1 Apr 2011

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Role of SLAM in NKT cell development revealed by transgenic complementation in NOD mice.

Journal of immunology (Baltimore, Md. : 1950); 186(7) pg3953-65

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Polysaccharides isolated from AÃ§aÃ fruit induce innate immune responses.

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28 Feb 2011

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Lowering glycosphingolipid levels in CD4+ T cells attenuates T cell receptor signaling, cytokine production, and differentiation to the Th17 lineage.

The Journal of Biological Chemistry; 286(17) pg14787-94

29 Apr 2011

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Impaired thymic tolerance to Î±-myosin directs autoimmunity to the heart in mice and humans.

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Generation and evaluation of an IPTG-regulated version of Vav-gene promoter for mouse transgenesis.

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21 Mar 2011

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Enhanced transduction and replication of RGD-fiber modified adenovirus in primary T cells.

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28 Mar 2011

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The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells.

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Journal of immunology (Baltimore, Md. : 1950); 186(10) pg5791-800

15 May 2011

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An aberrant thymus in CCR5-/- mice is coupled with an enhanced adaptive immune response in fungal infection.

Journal of immunology (Baltimore, Md. : 1950); 186(10) pg5949-55

15 May 2011

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IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo.

Journal of immunology (Baltimore, Md. : 1950); 186(11) pg6329-37

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DX5+NKT cells display phenotypical and functional differences between spleen and liver as well as NK1.1-Balb/c and NK1.1+ C57Bl/6 mice.

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26 Apr 2011

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The Journal of Experimental Medicine; 208(6) pg1163-77

6 Jun 2011

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Expression of miRNAs miR-133b and miR-206 in the Il17a/f locus is co-regulated with IL-17 production in Î±Î² and Î³Î´ T cells.

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IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors.

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Activated NKT cells and NK cells render T cells resistant to myeloid-derived suppressor cells and result in an effective adoptive cellular therapy against breast cancer in the FVBN202 transgenic mouse.

Journal of immunology (Baltimore, Md. : 1950); 187(2) pg708-17

15 Jul 2011

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Absence of Stat1 in donor CD4âº T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.

The Journal of Clinical Investigation; 121(7) pg2554-69

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Effector and naturally occurring regulatory T cells display no abnormalities in activation induced cell death in NOD mice.

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Chemokine receptor CXCR3 facilitates CD8(+) T cell differentiation into short-lived effector cells leading to memory degeneration.

The Journal of Experimental Medicine; 208(8) pg1605-20

1 Aug 2011

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Antiasthmatic drugs targeting the cysteinyl leukotriene receptor 1 alleviate central nervous system inflammatory cell infiltration and pathogenesis of experimental autoimmune encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950); 187(5) pg2336-45

1 Sep 2011

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Development and function of innate polyclonal TCRalphabeta+ CD8+ thymocytes.

Journal of immunology (Baltimore, Md. : 1950); 187(6) pg3133-44

15 Sep 2011

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Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction.

Journal of immunology (Baltimore, Md. : 1950); 187(6) pg3186-97

15 Sep 2011

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The liver kinase B1 is a central regulator of T cell development, activation, and metabolism.

Journal of immunology (Baltimore, Md. : 1950); 187(8) pg4187-98

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Invariant NKT cell defects in vitamin D receptor knockout mice prevents experimental lung inflammation.

Journal of immunology (Baltimore, Md. : 1950); 187(9) pg4907-12

1 Nov 2011

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GATA3 controls Foxp3âº regulatory T cell fate during inflammation in mice.

The Journal of Clinical Investigation; 121(11) pg4503-15

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Jiang, S

Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation.

Blood; 118(20) pg5487-97

17 Nov 2011

21972292
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Grigoriadis, G

c-Rel controls multiple discrete steps in the thymic development of Foxp3+ CD4 regulatory T cells.

PLoS ONE; 6(10) pge26851

0 2011

22066012
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Tang, Y

Emergence of NK-cell progenitors and functionally competent NK-cell lineage subsets in the early mouse embryo.

Blood; 120(1) pg63-75

5 Jul 2012

22072559
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LaCasse, C J

Th-1 lymphocytes induce dendritic cell tumor killing activity by an IFN-Î³-dependent mechanism.

Journal of immunology (Baltimore, Md. : 1950); 187(12) pg6310-7

15 Dec 2011

22075702
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Sela, U

Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice.

The Journal of Experimental Medicine; 208(12) pg2489-96

21 Nov 2011

22084406
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Mukai, Y

Induction of endoplasmic reticulum-endosome fusion for antigen cross-presentation induced by poly (Î³-glutamic acid) nanoparticles.

Journal of immunology (Baltimore, Md. : 1950); 187(12) pg6249-55

15 Dec 2011

22095716
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Khan, O

Regulation of T cell priming by lymphoid stroma.

PLoS ONE; 6(11) pge26138

0 2011

22110583
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Purtha, W E

Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants.

The Journal of Experimental Medicine; 208(13) pg2599-606

19 Dec 2011

22162833
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Goswami, R

STAT6-dependent regulation of Th9 development.

Journal of immunology (Baltimore, Md. : 1950); 188(3) pg968-75

1 Feb 2012

22180613
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Cuda, C M

Pre-B cell leukemia homeobox 1 is associated with lupus susceptibility in mice and humans.

Journal of immunology (Baltimore, Md. : 1950); 188(2) pg604-14

15 Jan 2012

22180614
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Chen, Y

Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression.

Journal of immunology (Baltimore, Md. : 1950); 188(4) pg1698-707

15 Feb 2012

22231701
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Loebbermann, J

Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection.

Mucosal Immunology; 5(2) pg161-72

0 Mar 2012

22236998
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Tischner, D

Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice.

Journal of Autoimmunity; 38(1) pg59-69

0 Feb 2012

22257939
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Yamaji, O

The development of colitogenic CD4(+) T cells is regulated by IL-7 in collaboration with NK cell function in a murine model of colitis.

Journal of immunology (Baltimore, Md. : 1950); 188(6) pg2524-36

15 Mar 2012

22331065
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Hu, J

Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.

Cell; 148(4) pg651-63

17 Feb 2012

22341440
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Zhang, B

Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model.

Cell; 148(4) pg739-51

17 Feb 2012

22341446
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Cedeno-Laurent, F

Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression.

Journal of immunology (Baltimore, Md. : 1950); 188(7) pg3127-37

1 Apr 2012

22345665
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Mei, H

Î²-defensin 2 as an adjuvant promotes anti-melanoma immune responses and inhibits the growth of implanted murine melanoma in vivo.

PLoS ONE; 7(2) pge31328

0 2012

22348070
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Friedman-Levi, Y

Targeting of prion-infected lymphoid cells to the central nervous system accelerates prion infection.

Journal of Neuroinflammation; 9 pg58

21 Mar 2012

22436404
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Attridge, K

IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis.

Blood; 119(20) pg4656-64

17 May 2012

22442347
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Uchiyama, M

Auditory stimulation of opera music induced prolongation of murine cardiac allograft survival and maintained generation of regulatory CD4+CD25+ cells.

Journal of Cardiothoracic Surgery; 7 pg26

23 Mar 2012

22445281
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Wortham, B W

NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease.

Journal of immunology (Baltimore, Md. : 1950); 188(9) pg4468-75

1 May 2012

22467655
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Cui, N

Effective adoptive transfer of haploidentical tumor-specific T cells in B16-melanoma bearing mice.

Chinese Medical Journal; 125(5) pg794-800

0 Mar 2012

22490577
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Mycko, M P

MicroRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination.

Proceedings of the National Academy of Sciences of the United States of America; 109(20) pgE1248-57

15 May 2012

22517757
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Ma, J

Protein kinase C-Î¸ inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway.

Journal of immunology (Baltimore, Md. : 1950); 188(11) pg5337-47

1 Jun 2012

22539794
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Abdi, K

Lipopolysaccharide-activated dendritic cells: "exhausted" or alert and waiting?

Journal of immunology (Baltimore, Md. : 1950); 188(12) pg5981-9

15 Jun 2012

22561154
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Souza-Fonseca-Guimaraes, F

NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis.

Journal of immunology (Baltimore, Md. : 1950); 188(12) pg5850-8

15 Jun 2012

22566566
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Ottina, E

Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice.

Blood; 119(25) pg6032-42

21 Jun 2012

22581448
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Thomas, R M

De novo DNA methylation is required to restrict T helper lineage plasticity.

The Journal of Biological Chemistry; 287(27) pg22900-9

29 Jun 2012

22584578
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Andersen, K G

Comparative Genomics Reveals Key Gain-of-Function Events in Foxp3 during Regulatory T Cell Evolution.

Frontiers in Immunology; 3 pg113

0 2012

22590469
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Shankar, S P

RGS16 attenuates pulmonary Th2/Th17 inflammatory responses.

Journal of immunology (Baltimore, Md. : 1950); 188(12) pg6347-56

15 Jun 2012

22593615
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Gupta, S

Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs.

The Journal of Clinical Investigation; 122(7) pg2395-404

0 Jul 2012

22684103
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Lin, Y

Transcriptional regulator Id2 is required for the CD4 T cell immune response in the development of experimental autoimmune encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950); 189(3) pg1400-5

1 Aug 2012

22745378
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Poovassery, J S

Type I IFN receptor and the B cell antigen receptor regulate TLR7 responses via distinct molecular mechanisms.

Journal of immunology (Baltimore, Md. : 1950); 189(4) pg1757-64

15 Aug 2012

22786773
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Gallo, R M

Regulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d.

Journal of immunology (Baltimore, Md. : 1950); 189(4) pg1689-98

15 Aug 2012

22798677
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Jin, X

Inchingorei-san (TJ-117) and Artemisiae Capillaris Herba Induced Prolonged Survival of Fully Mismatched Cardiac Allografts and Generated Regulatory Cells in Mice.

Evidence-based complementary and alternative medicine : eCAM; 2012 pg689810

0 2012

22811750
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Kwon, K W

Nanotopography-guided migration of T cells.

Journal of immunology (Baltimore, Md. : 1950); 189(5) pg2266-73

1 Sep 2012

22844118
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Hu, P

p38Î± protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals.

The Journal of Biological Chemistry; 287(40) pg33215-26

28 Sep 2012

22859305
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Kinoshita, M

Dietary folic acid promotes survival of Foxp3+ regulatory T cells in the colon.

Journal of immunology (Baltimore, Md. : 1950); 189(6) pg2869-78

15 Sep 2012

22869901
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Schlenner, S M

Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut.

The Journal of Experimental Medicine; 209(9) pg1529-35

27 Aug 2012

22908322
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Dervovic, D D

Comparative and functional evaluation of in vitro generated to ex vivo CD8 T cells.

Journal of immunology (Baltimore, Md. : 1950); 189(7) pg3411-20

1 Oct 2012

22925927
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Le Campion, A

IL-2 and IL-7 determine the homeostatic balance between the regulatory and conventional CD4+ T cell compartments during peripheral T cell reconstitution.

Journal of immunology (Baltimore, Md. : 1950); 189(7) pg3339-46

1 Oct 2012

22933631
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Vigne, S

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.

Blood; 120(17) pg3478-87

25 Oct 2012

22968459
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Ramalingam, R

Dendritic cell-specific disruption of TGF-Î² receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity.

Journal of immunology (Baltimore, Md. : 1950); 189(8) pg3878-93

15 Oct 2012

22972928
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Regateiro, F S

Foxp3 expression is required for the induction of therapeutic tissue tolerance.

Journal of immunology (Baltimore, Md. : 1950); 189(8) pg3947-56

15 Oct 2012

22988034
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Zandi, S

Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo.

Proceedings of the National Academy of Sciences of the United States of America; 109(39) pg15871-6

25 Sep 2012

23019372
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Rafei, M

Differential effects of Î³c cytokines on postselection differentiation of CD8 thymocytes.

Blood; 121(1) pg107-17

3 Jan 2013

23043071
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Perona-Wright, G

Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response.

Proceedings of the National Academy of Sciences of the United States of America; 109(45) pg18535-40

6 Nov 2012

23091017
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Yao, R

MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1.

PLoS ONE; 7(10) pge46082

0 2012

23091595
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Fiorenza, S

A combination of local inflammation and central memory T cells potentiates immunotherapy in the skin.

Journal of immunology (Baltimore, Md. : 1950); 189(12) pg5622-31

15 Dec 2012

23144496
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Link, J M

A critical role for Mnt in Myc-driven T-cell proliferation and oncogenesis.

Proceedings of the National Academy of Sciences of the United States of America; 109(48) pg19685-90

27 Nov 2012

23150551
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Chinnery, F

Viral antigen mediated NKp46 activation of NK cells results in tumor rejection via NK-DC crosstalk.

Oncoimmunology; 1(6) pg874-883

1 Sep 2012

23162755
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Collins, S

Regulation of CD4âº and CD8âº effector responses by Sprouty-1.

PLoS ONE; 7(11) pge49801

0 2012

23166773
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Kanagawa, N

Tumor vessel-injuring ability improves antitumor effect of cytotoxic T lymphocytes in adoptive immunotherapy.

Cancer Gene Therapy; 20(1) pg57-64

0 Jan 2013

23175243
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Devey, L R

Ischemic preconditioning in the liver is independent of regulatory T cell activity.

PLoS ONE; 7(11) pge49647

0 2012

23185394
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Kim, S H

Rheumatoid Fibroblast-like Synoviocytes Downregulate Foxp3 Expression by Regulatory T Cells Via GITRL/GITR Interaction.

Immune Network; 12(5) pg217-21

0 Oct 2012

23213316
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Loebbermann, J

Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cells.

Proceedings of the National Academy of Sciences of the United States of America; 110(8) pg2987-92

19 Feb 2013

23382205
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Singh, K

Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis.

Journal of immunology (Baltimore, Md. : 1950); 190(6) pg2544-53

15 Mar 2013

23418628
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Guo, Z

A dynamic dual role of IL-2 signaling in the two-step differentiation process of adaptive regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 190(7) pg3153-62

1 Apr 2013

23427250
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Borger, J G

Differential polarization of C-terminal Src kinase between naive and antigen-experienced CD8+ T cells.

Journal of immunology (Baltimore, Md. : 1950); 190(7) pg3089-99

1 Apr 2013

23427257
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Souza-Fonseca-Guimaraes, F

Interferon-Î³ and granulocyte/monocyte colony-stimulating factor production by natural killer cells involves different signaling pathways and the adaptor stimulator of interferon genes (STING).

The Journal of Biological Chemistry; 288(15) pg10715-21

12 Apr 2013

23443666
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Behrends, J

IL-22 is mainly produced by IFNÎ³-secreting cells but is dispensable for host protection against Mycobacterium tuberculosis infection.

PLoS ONE; 8(2) pge57379

0 2013

23460846
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Jia, Y

Stepwise epigenetic and phenotypic alterations poise CD8+ T cells to mediate airway hyperresponsiveness and inflammation.

Journal of immunology (Baltimore, Md. : 1950); 190(8) pg4056-65

15 Apr 2013

23509358
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Han, S

Adiponectin deficiency suppresses lymphoma growth in mice by modulating NK cells, CD8 T cells, and myeloid-derived suppressor cells.

Journal of immunology (Baltimore, Md. : 1950); 190(9) pg4877-86

1 May 2013

23530146
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Edwards, J P

Regulation of the expression of GARP/latent TGF-Î²1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation.

Journal of immunology (Baltimore, Md. : 1950); 190(11) pg5506-15

1 Jun 2013

23645881
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Gasteiger, G

IL-2-dependent adaptive control of NK cell homeostasis.

The Journal of Experimental Medicine; 210(6) pg1179-87

3 Jun 2013

23650439
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Gasteiger, G

IL-2-dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells.

The Journal of Experimental Medicine; 210(6) pg1167-78

3 Jun 2013

23650441
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Sakai, Y

The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation.

Blood; 122(3) pg386-93

18 Jul 2013

23719299
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Li, J

Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice.

Journal of immunology (Baltimore, Md. : 1950); 191(1) pg200-7

1 Jul 2013

23729441
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Holmgaard, R B

Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4.

The Journal of Experimental Medicine; 210(7) pg1389-402

1 Jul 2013

23752227
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Yamashita, J

Paraoxonase-1 suppresses experimental colitis via the inhibition of IFN-Î³ production from CD4 T cells.

Journal of immunology (Baltimore, Md. : 1950); 191(2) pg949-60

15 Jul 2013

23772025
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Tamiya, T

Smad2/3 and IRF4 play a cooperative role in IL-9-producing T cell induction.

Journal of immunology (Baltimore, Md. : 1950); 191(5) pg2360-71

1 Sep 2013

23913959
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Pierini, R

ASC controls IFN-Î³ levels in an IL-18-dependent manner in caspase-1-deficient mice infected with Francisella novicida.

Journal of immunology (Baltimore, Md. : 1950); 191(7) pg3847-57

1 Oct 2013

23975862
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Takeuchi, H

Retinoid X receptor agonists modulate Foxp3âº regulatory T cell and Th17 cell differentiation with differential dependence on retinoic acid receptor activation.

Journal of immunology (Baltimore, Md. : 1950); 191(7) pg3725-33

1 Oct 2013

23980207
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Frazer, L C

CD4+ T cell expression of MyD88 is essential for normal resolution of Chlamydia muridarum genital tract infection.

Journal of immunology (Baltimore, Md. : 1950); 191(8) pg4269-79

15 Oct 2013

24038087
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Lo, Y

Selective activation of antigen-experienced T cells by anti-CD3 constrained on nanoparticles.

Journal of immunology (Baltimore, Md. : 1950); 191(10) pg5107-14

15 Nov 2013

24098054
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Cho, J

Unique features of naive CD8+ T cell activation by IL-2.

Journal of immunology (Baltimore, Md. : 1950); 191(11) pg5559-73

1 Dec 2013

24166977
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Okiyama, N

Reversal of CD8 T-cell-mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib.

The Journal of Investigative Dermatology; 134(4) pg992-1000

0 Apr 2014

24213371
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Lee, P

The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineage.

Journal of immunology (Baltimore, Md. : 1950); 192(1) pg178-88

1 Jan 2014

24259505
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McNally, J P

Eliminating encephalitogenic T cells without undermining protective immunity.

Journal of immunology (Baltimore, Md. : 1950); 192(1) pg73-83

1 Jan 2014

24277699
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Ogawa, C

TGF-Î²-mediated Foxp3 gene expression is cooperatively regulated by Stat5, Creb, and AP-1 through CNS2.

Journal of immunology (Baltimore, Md. : 1950); 192(1) pg475-83

1 Jan 2014

24298014
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Starbeck-Miller, G R

IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo.

The Journal of Experimental Medicine; 211(1) pg105-20

13 Jan 2014

24367005
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Thestrup, T

Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes.

Nature Methods; 11(2) pg175-82

0 Feb 2014

24390440
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Ling, G S

Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages.

Nature Communications; 5 pg3039

0 2014

24423728
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Li, H

CCR7 guides migration of mesenchymal stem cell to secondary lymphoid organs: a novel approach to separate GvHD from GvL effect.

Stem cells (Dayton, Ohio); 32(7) pg1890-903

0 Jul 2014

24496849
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Mackenzie, K J

Effector and central memory T helper 2 cells respond differently to peptide immunotherapy.

Proceedings of the National Academy of Sciences of the United States of America; 111(8) pgE784-93

25 Feb 2014

24516158
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Gomez-Rodriguez, J

Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells.

The Journal of Experimental Medicine; 211(3) pg529-43

10 Mar 2014

24534190
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Kobayashi, C I

The IL-2/CD25 axis maintains distinct subsets of chronic myeloid leukemia-initiating cells.

Blood; 123(16) pg2540-9

17 Apr 2014

24574458
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Vaeth, M

Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.

The Journal of Experimental Medicine; 211(3) pg545-61

10 Mar 2014

24590764
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Male, V

The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression.

The Journal of Experimental Medicine; 211(4) pg635-42

7 Apr 2014

24663216
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Cortez, V S

CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection.

The Journal of Experimental Medicine; 211(4) pg623-33

7 Apr 2014

24687959
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Zarin, P

Enforcement of Î³Î´-lineage commitment by the pre-T-cell receptor in precursors with weak Î³Î´-TCR signals.

Proceedings of the National Academy of Sciences of the United States of America; 111(15) pg5658-63

15 Apr 2014

24706811
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Srivastava, S

Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection.

The Journal of Experimental Medicine; 211(5) pg961-74

5 May 2014

24711580
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Klose, C S

Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages.

Cell; 157(2) pg340-356

10 Apr 2014

24725403
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Kumar, L

Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function.

The Journal of Experimental Medicine; 211(5) pg929-42

5 May 2014

24752297
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Nair, S K

High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes.

Scientific Reports; 4 pg4632

23 Apr 2014

24755960
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O'Brien, S

Ikaros imposes a barrier to CD8+ T cell differentiation by restricting autocrine IL-2 production.

Journal of immunology (Baltimore, Md. : 1950); 192(11) pg5118-29

1 Jun 2014

24778448
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Crites, T J

TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction.

Journal of immunology (Baltimore, Md. : 1950); 193(1) pg56-67

1 Jul 2014

24860189
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Glenn, J D

Mesenchymal stem cells differentially modulate effector CD8+ T cell subsets and exacerbate experimental autoimmune encephalomyelitis.

Stem cells (Dayton, Ohio); 32(10) pg2744-55

0 Oct 2014

24911892
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Madireddi, S

Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.

The Journal of Experimental Medicine; 211(7) pg1433-48

30 Jun 2014

24958847
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Kissick, H T

Androgens alter T-cell immunity by inhibiting T-helper 1 differentiation.

Proceedings of the National Academy of Sciences of the United States of America; 111(27) pg9887-92

8 Jul 2014

24958858
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Li, C

MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation.

Proceedings of the National Academy of Sciences of the United States of America; 111(27) pgE2807-16

8 Jul 2014

24958888
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Longman, R S

CXâ‚ƒCR1âº mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.

The Journal of Experimental Medicine; 211(8) pg1571-83

28 Jul 2014

25024136
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Okoye, I S

Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity.

Proceedings of the National Academy of Sciences of the United States of America; 111(30) pgE3081-90

29 Jul 2014

25024218
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Deho', L

Two functionally distinct subsets of mast cells discriminated By IL-2-independent CD25 activities.

Journal of immunology (Baltimore, Md. : 1950); 193(5) pg2196-206

1 Sep 2014

25063866
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Huang, W

IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive function.

Journal of immunology (Baltimore, Md. : 1950); 193(5) pg2267-72

1 Sep 2014

25063868
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Seillet, C

Nfil3 is required for the development of all innate lymphoid cell subsets.

The Journal of Experimental Medicine; 211(9) pg1733-40

25 Aug 2014

25092873
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Tilahun, A Y

Systemic inflammatory response elicited by superantigen destabilizes T regulatory cells, rendering them ineffective during toxic shock syndrome.

Journal of immunology (Baltimore, Md. : 1950); 193(6) pg2919-30

15 Sep 2014

25092888
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Ehrlich, A

The immunotherapeutic role of regulatory T cells in Leishmania (Viannia) panamensis infection.

Journal of immunology (Baltimore, Md. : 1950); 193(6) pg2961-70

15 Sep 2014

25098291
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Rei, M

Murine CD27(-) VÎ³6(+) Î³Î´ T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages.

Proceedings of the National Academy of Sciences of the United States of America; 111(34) pgE3562-70

26 Aug 2014

25114209
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Sundberg, T B

Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.

Proceedings of the National Academy of Sciences of the United States of America; 111(34) pg12468-73

26 Aug 2014

25114223
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Degryse, S

JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.

Blood; 124(20) pg3092-100

13 Nov 2014

25193870
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Brennan, P J

Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction.

Proceedings of the National Academy of Sciences of the United States of America; 111(37) pg13433-8

16 Sep 2014

25197085
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Chu, C

SAP-regulated T Cell-APC adhesion and ligation-dependent and -independent Ly108-CD3Î¶ interactions.

Journal of immunology (Baltimore, Md. : 1950); 193(8) pg3860-71

15 Oct 2014

25217164
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Van der Meulen, J

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia.

Blood; 125(1) pg13-21

1 Jan 2015

25320243
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Chevalier, N

Inflammation and lymphopenia trigger autoimmunity by suppression of IL-2-controlled regulatory T cell and increase of IL-21-mediated effector T cell expansion.

Journal of immunology (Baltimore, Md. : 1950); 193(10) pg4845-58

15 Nov 2014

25339665
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Tang, W

The oncoprotein and transcriptional regulator Bcl-3 governs plasticity and pathogenicity of autoimmune T cells.

Immunity; 41(4) pg555-66

16 Oct 2014

25367572
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Eun, S

4-1BB ligand signaling to T cells limits T cell activation.

Journal of immunology (Baltimore, Md. : 1950); 194(1) pg134-41

1 Jan 2015

25404362
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Gaddipati, S

IL-2/anti-IL-2 antibody complex treatment inhibits the development but not the progression of herpetic stromal keratitis.

Journal of immunology (Baltimore, Md. : 1950); 194(1) pg273-82

1 Jan 2015

25411200
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Waight, J D

Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans.

Journal of immunology (Baltimore, Md. : 1950); 194(3) pg878-82

1 Feb 2015

25548231
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Mackay, L K

Cutting edge: CD69 interference with sphingosine-1-phosphate receptor function regulates peripheral T cell retention.

Journal of immunology (Baltimore, Md. : 1950); 194(5) pg2059-63

1 Mar 2015

25624457
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Zheng, Y

Photodynamic therapy-mediated cancer vaccination enhances stem-like phenotype and immune escape, which can be blocked by thrombospondin-1 signaling through CD47 receptor protein.

The Journal of Biological Chemistry; 290(14) pg8975-86

3 Apr 2015

25697354
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Vogel, S Z

TCAIM decreases T cell priming capacity of dendritic cells by inhibiting TLR-induced Ca2+ influx and IL-2 production.

Journal of immunology (Baltimore, Md. : 1950); 194(7) pg3136-46

1 Apr 2015

25750433
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Metidji, A

IFN-Î±/Î² receptor signaling promotes regulatory T cell development and function under stress conditions.

Journal of immunology (Baltimore, Md. : 1950); 194(9) pg4265-76

1 May 2015

25795758
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McCracken, M N

Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.

The Journal of Clinical Investigation; 125(5) pg1815-26

0 May 2015

25822024
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Baumann, C

T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses.

Proceedings of the National Academy of Sciences of the United States of America; 112(13) pg4056-61

31 Mar 2015

25829541
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del Blanco, B

T-cell receptor Î± enhancer is inactivated in Î±Î² T lymphocytes.

Proceedings of the National Academy of Sciences of the United States of America; 112(14) pgE1744-53

7 Apr 2015

25831496
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Schlie, K

Survival of effector CD8+ T cells during influenza infection is dependent on autophagy.

Journal of immunology (Baltimore, Md. : 1950); 194(9) pg4277-86

1 May 2015

25833396
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Ebel, M E

Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38Î± MAPK.

Journal of immunology (Baltimore, Md. : 1950); 194(12) pg5781-8

15 Jun 2015

25941329
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Li, Q

Regulatory Rebound in IL-12-Treated Tumors Is Driven by Uncommitted Peripheral Regulatory T Cells.

Journal of immunology (Baltimore, Md. : 1950); 195(3) pg1293-300

1 Aug 2015

26085681
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Suzuki, M

Spred1, a Suppressor of the Ras-ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells.

Journal of immunology (Baltimore, Md. : 1950); 195(3) pg1273-81

1 Aug 2015

26116510
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Sekiya, T

Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells.

The Journal of Experimental Medicine; 212(10) pg1623-40

21 Sep 2015

26304965
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Wang, C

CD8(+)NKT-like cells regulate the immune response by killing antigen-bearing DCs.

Scientific Reports; 5 pg14124

15 Sep 2015

26369936
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Kim, M T

Enhancing Dendritic Cell-based Immunotherapy with IL-2/Monoclonal Antibody Complexes for Control of Established Tumors.

Journal of immunology (Baltimore, Md. : 1950); 195(9) pg4537-44

1 Nov 2015

26408669
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Li, B

Immunodominant epitope-specific Th1 but not Th17 responses mediate protection against Helicobacter pylori infection following UreB vaccination of BALB/c mice.

Scientific Reports; 5 pg14793

5 Oct 2015

26434384
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Schmaler, M

IL-7R signaling in regulatory T cells maintains peripheral and allograft tolerance in mice.

Proceedings of the National Academy of Sciences of the United States of America; 112(43) pg13330-5

27 Oct 2015

26450881
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Manirarora, J N

Combination Therapy Using IL-2/IL-2 Monoclonal Antibody Complexes, Rapamycin, and Islet Autoantigen Peptides Increases Regulatory T Cell Frequency and Protects against Spontaneous and Induced Type 1 Diabetes in Nonobese Diabetic Mice.

Journal of immunology (Baltimore, Md. : 1950); 195(11) pg5203-14

1 Dec 2015

26482409
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Zhang, Z

DNAM-1 controls NK cell activation via an ITT-like motif.

The Journal of Experimental Medicine; 212(12) pg2165-82

16 Nov 2015

26552706
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Chan, S

Calcium-Modulating Cyclophilin Ligand Is Essential for the Survival of Activated T Cells and for Adaptive Immunity.

Journal of immunology (Baltimore, Md. : 1950); 195(12) pg5648-56

15 Dec 2015

26561552
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Song, Y

Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development.

Journal of immunology (Baltimore, Md. : 1950); 196(1) pg232-43

1 Jan 2016

26608918
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Yan, D

Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3.

Proceedings of the National Academy of Sciences of the United States of America; 112(48) pg14942-7

1 Dec 2015

26627244
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Yin, J

Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity.

Proceedings of the National Academy of Sciences of the United States of America; 112(52) pg15988-93

29 Dec 2015

26668377
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Herter, J M

AKAP9 regulates activation-induced retention of T lymphocytes at sites of inflammation.

Nature Communications; 6 pg10182

18 Dec 2015

26680259
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Everts, B

Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12.

The Journal of Experimental Medicine; 213(1) pg35-51

11 Jan 2016

26712805
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Kimmerling, R J

A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages.

Nature Communications; 7 pg10220

6 Jan 2016

26732280
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Delconte, R B

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.

Immunity; 44(1) pg103-115

19 Jan 2016

26795246
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Sasidharan Nair, V

Vitamin C Facilitates Demethylation of the Foxp3 Enhancer in a Tet-Dependent Manner.

Journal of immunology (Baltimore, Md. : 1950); 196(5) pg2119-31

1 Mar 2016

26826239
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Cho, S

miR-23âˆ¼27âˆ¼24 clusters control effector T cell differentiation and function.

The Journal of Experimental Medicine; 213(2) pg235-49

8 Feb 2016

26834155
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Mascarenhas, M I

Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation.

Blood; 127(19) pg2298-309

12 May 2016

26864339
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Akane, K

CD8+CD122+CD49dlow regulatory T cells maintain T-cell homeostasis by killing activated T cells via Fas/FasL-mediated cytotoxicity.

Proceedings of the National Academy of Sciences of the United States of America; 113(9) pg2460-5

1 Mar 2016

26869716
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Hecht, V C

Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes.

The Journal of Cell Biology; 212(4) pg439-47

15 Feb 2016

26880201
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Jones, L L

Differential T Cell Cytokine Receptivity and Not Signal Quality Distinguishes IL-6 and IL-10 Signaling during Th17 Differentiation.

Journal of immunology (Baltimore, Md. : 1950); 196(7) pg2973-85

1 Apr 2016

26912317
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Radtke, D

Grb2 Is Important for T Cell Development, Th Cell Differentiation, and Induction of Experimental Autoimmune Encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950); 196(7) pg2995-3005

1 Apr 2016

26921310
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Barros-Martins, J

Effector Î³Î´ T Cell Differentiation Relies on Master but Not Auxiliary Th Cell Transcription Factors.

Journal of immunology (Baltimore, Md. : 1950); 196(9) pg3642-52

1 May 2016

26994218
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Song, K H

Roles of endothelial A-type lamins in migration of T cells on and under endothelial layers.

Scientific Reports; 6 pg23412

21 Mar 2016

26996137
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Kourepini, E

TIGIT Enhances Antigen-Specific Th2 Recall Responses and Allergic Disease.

Journal of immunology (Baltimore, Md. : 1950); 196(9) pg3570-80

1 May 2016

27016609
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Pasi, S

Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response.

The Journal of Biological Chemistry; 291(23) pg12358-69

3 Jun 2016

27022030
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Zhang, Z

Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice.

Scientific Reports; 6 pg23912

5 Apr 2016

27045575
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Rabacal, W

Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival.

Proceedings of the National Academy of Sciences of the United States of America; 113(19) pg5370-5

10 May 2016

27114551
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Cortez, V S

Transforming Growth Factor-Î² Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands.

Immunity; 44(5) pg1127-39

17 May 2016

27156386
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Cooley, L F

Impaired immunological synapse in sperm associated antigen 6 (SPAG6) deficient mice.

Scientific Reports; 6 pg25840

12 May 2016

27169488
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Verrier, T

Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells.

Journal of immunology (Baltimore, Md. : 1950); 196(11) pg4731-8

1 Jun 2016

27183613
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Aggelakopoulou, M

ERÎ² in CD4+ T Cells Is Crucial for Ligand-Mediated Suppression of Central Nervous System Autoimmunity.

Journal of immunology (Baltimore, Md. : 1950); 196(12) pg4947-56

15 Jun 2016

27183630
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Krausgruber, T

T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine.

Nature Communications; 7 pg11627

19 May 2016

27193261
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Kawalkowska, J

Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses.

Scientific Reports; 6 pg26430

23 May 2016

27210478
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Choi, S

The Lupus Susceptibility Gene Pbx1 Regulates the Balance between Follicular Helper T Cell and Regulatory T Cell Differentiation.

Journal of immunology (Baltimore, Md. : 1950); 197(2) pg458-69

15 Jul 2016

27296664
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Chou, T

Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1Î± for Th17 suppression.

Nature Communications; 7 pg11904

17 Jun 2016

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Ichiyama, K

The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression.

Immunity; 44(6) pg1284-98

21 Jun 2016

27332731
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Chen, L C

A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells.

Journal of immunology (Baltimore, Md. : 1950); 197(4) pg1137-47

15 Aug 2016

27402696
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Liu, L

Integrated Nanovaccine with MicroRNA-148a Inhibition Reprograms Tumor-Associated Dendritic Cells by Modulating miR-148a/DNMT1/SOCS1 Axis.

Journal of immunology (Baltimore, Md. : 1950); 197(4) pg1231-41

15 Aug 2016

27421476
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Manipulating Memory CD8 T Cell Numbers by Timed Enhancement of IL-2 Signals.

Journal of immunology (Baltimore, Md. : 1950); 197(5) pg1754-61

1 Sep 2016

27439516
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IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo.

Scientific Reports; 6 pg30636

1 Aug 2016

27477778
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Cheng, H

Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis.

The Journal of Clinical Investigation; 126(9) pg3236-46

1 Sep 2016

27482882
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Leclerc, M

Control of GVHD by regulatory T cells depends on TNF produced by T cells and TNFR2 expressed by regulatory T cells.

Blood; 128(12) pg1651-9

22 Sep 2016

27506541
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Network pharmacology of JAK inhibitors.

Proceedings of the National Academy of Sciences of the United States of America; 113(35) pg9852-7

30 Aug 2016

27516546
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Aggelakopoulou, M

ERÎ²-Dependent Direct Suppression of Human and Murine Th17 Cells and Treatment of Established Central Nervous System Autoimmunity by a Neurosteroid.

Journal of immunology (Baltimore, Md. : 1950); 197(7) pg2598-609

1 Oct 2016

27549171
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Pageon, S V

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination.

Proceedings of the National Academy of Sciences of the United States of America; 113(37) pgE5454-63

13 Sep 2016

27573839
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Byeon, H

Hybrid bright-field and hologram imaging of cell dynamics.

Scientific Reports; 6 pg33750

19 Sep 2016

27640337
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Lexmond, W S

FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy.

The Journal of Clinical Investigation; 126(10) pg4030-4044

3 Oct 2016

27643438
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Morillon, Y M

Antibody Binding to CD4 Induces Rac GTPase Activation and Alters T Cell Migration.

Journal of immunology (Baltimore, Md. : 1950); 197(9) pg3504-3511

1 Nov 2016

27694496
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Sochalska, M

MYC selects against reduced BCL2A1/A1 protein expression during B cell lymphomagenesis.

Oncogene; 36(15) pg2066-2073

0 Apr 2017

27694901
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Chu, V T

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.

Proceedings of the National Academy of Sciences of the United States of America; 113(44) pg12514-12519

1 Nov 2016

27729526
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Mundy-Bosse, B L

MicroRNA-29b mediates altered innate immune development in acute leukemia.

The Journal of Clinical Investigation; 126(12) pg4404-4416

1 Dec 2016

27775550
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Cho, J

CD45-mediated control of TCR tuning in naÃ¯ve and memory CD8

Nature Communications; 7 pg13373

14 Nov 2016

27841348
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Lee, W W

Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice.

Scientific Reports; 6 pg37603

25 Nov 2016

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Jin, R M

Regulatory T Cells Promote Myositis and Muscle Damage in Toxoplasma gondii Infection.

Journal of immunology (Baltimore, Md. : 1950); 198(1) pg352-362

1 Jan 2017

27895180
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Van de Velde, L

T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions.

The Journal of Biological Chemistry; 292(1) pg15-30

6 Jan 2017

27903651
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Inoo, K

Immunological quality and performance of tumor vessel-targeting CAR-T cells prepared by mRNA-EP for clinical research.

Molecular therapy oncolytics; 3 pg16024

0 2016

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Hayakawa, M

Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction.

The Journal of Biological Chemistry; 292(5) pg1762-1772

3 Feb 2017

28011639
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Viant, C

Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival.

The Journal of Experimental Medicine; 214(2) pg491-510

0 Feb 2017

28057804
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Stephen, T L

SATB1 Expression Governs Epigenetic Repression of PD-1 in Tumor-Reactive T Cells.

Immunity; 46(1) pg51-64

17 Jan 2017

28099864
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Vaeth, M

ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.

Nature Communications; 8 pg14714

15 Mar 2017

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Fu, G

Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1.

The Journal of Experimental Medicine; 214(5) pg1453-1469

1 May 2017

28400474
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Chien, C

Characterization of c-Maf

Scientific Reports; 7 pg46348

12 Apr 2017

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Klann, J E

Talin Plays a Critical Role in the Maintenance of the Regulatory T Cell Pool.

Journal of immunology (Baltimore, Md. : 1950); 198(12) pg4639-4651

15 Jun 2017

28515282
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Takahashi, R

SOCS1 Is a Key Molecule That Prevents Regulatory T Cell Plasticity under Inflammatory Conditions.

Journal of immunology (Baltimore, Md. : 1950); 199(1) pg149-158

1 Jul 2017

28550203
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Onodera, A

Menin Controls the Memory Th2 Cell Function by Maintaining the Epigenetic Integrity of Th2 Cells.

Journal of immunology (Baltimore, Md. : 1950); 199(3) pg1153-1162

1 Aug 2017

28659357
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Chen, J

The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells.

The Journal of Biological Chemistry; 292(35) pg14532-14543

1 Sep 2017

28684423
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Wang, Q

Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability.

Scientific Reports; 7(1) pg6086

20 Jul 2017

28729608
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Goel, S

CDK4/6 inhibition triggers anti-tumour immunity.

Nature; 548(7668) pg471-475

24 Aug 2017

28813415
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Corpuz, T M

IL-2 Shapes the Survival and Plasticity of IL-17-Producing Î³Î´ T Cells.

Journal of immunology (Baltimore, Md. : 1950); 199(7) pg2366-2376

1 Oct 2017

28835458
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Salerno, F

Distinct PKC-mediated posttranscriptional events set cytokine production kinetics in CD8

Proceedings of the National Academy of Sciences of the United States of America; 114(36) pg9677-9682

5 Sep 2017

28835535
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Wang, S

Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.

Cell; 171(1) pg201-216.e18

21 Sep 2017

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Widjaja, C E

Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.

The Journal of Clinical Investigation; 127(10) pg3609-3623

2 Oct 2017

28846070
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Oh, H

An NF-ÎºB Transcription-Factor-Dependent Lineage-Specific Transcriptional Program Promotes Regulatory T Cell Identity and Function.

Immunity; 47(3) pg450-465.e5

19 Sep 2017

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Ottina, E

DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice.

Nature Communications; 8(1) pg1028

18 Oct 2017

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Taghavie-Moghadam, P L

STAT4 Regulates the CD8

Journal of immunology (Baltimore, Md. : 1950); 199(10) pg3453-3465

15 Nov 2017

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Ko, J S

Palmitate inhibits arthritis by inducing t-bet and gata-3 mRNA degradation in iNKT cells via IRE1Î±-dependent decay.

Scientific Reports; 7(1) pg14940

2 Nov 2017

29097726
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Kotani, T

Anti-inflammatory and anti-fibrotic effects of intravenous adipose-derived stem cell transplantation in a mouse model of bleomycin-induced interstitial pneumonia.

Scientific Reports; 7(1) pg14608

6 Nov 2017

29097816
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Polesso, F

Constitutive expression of NF-ÎºB inducing kinase in regulatory T cells impairs suppressive function and promotes instability and pro-inflammatory cytokine production.

Scientific Reports; 7(1) pg14779

7 Nov 2017

29116141
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Schmid, D

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity.

Nature Communications; 8(1) pg1747

23 Nov 2017

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Wu, J

Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4

Immunity; 47(6) pg1114-1128.e6

19 Dec 2017

29221730
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Stier, M T

IL-33 promotes the egress of group 2 innate lymphoid cells from the bone marrow.

The Journal of Experimental Medicine; 215(1) pg263-281

2 Jan 2018

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Zhang, Y

Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity.

Nature Communications; 9(1) pg6

2 Jan 2018

29295974
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Kim, D

Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis.

Nature Communications; 9(1) pg503

5 Feb 2018

29403003
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Guan, T

ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8

The Journal of Experimental Medicine; 215(4) pg1153-1168

2 Apr 2018

29449309
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Grinberg-Bleyer, Y

The Alternative NF-ÎºB Pathway in Regulatory T Cell Homeostasis and Suppressive Function.

Journal of immunology (Baltimore, Md. : 1950); 200(7) pg2362-2371

1 Apr 2018

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Yu, W

Protective humoral and CD4

Scientific Reports; 8(1) pg3580

26 Feb 2018

29483570
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Chen, D

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.

Nature Communications; 9(1) pg873

28 Feb 2018

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Menk, A V

4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses.

The Journal of Experimental Medicine; 215(4) pg1091-1100

2 Apr 2018

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Bhatt, B

Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation.

Journal of immunology (Baltimore, Md. : 1950); 200(8) pg2905-2914

15 Apr 2018

29514953
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Stanko, K

CD96 expression determines the inflammatory potential of IL-9-producing Th9 cells.

Proceedings of the National Academy of Sciences of the United States of America; 115(13) pgE2940-E2949

27 Mar 2018

29531070
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Choi, S

Relative Contributions of B Cells and Dendritic Cells from Lupus-Prone Mice to CD4

Journal of immunology (Baltimore, Md. : 1950); 200(9) pg3087-3099

1 May 2018

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Antigen-Induced but Not Innate Memory CD8 T Cells Express NKG2D and Are Recruited to the Lung Parenchyma upon Viral Infection.

Journal of immunology (Baltimore, Md. : 1950); 200(10) pg3635-3646

15 May 2018

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Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo.

Nature Communications; 9(1) pg1325

10 Apr 2018

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Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28.

Nature Communications; 9(1) pg1424

12 Apr 2018

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Critical role of OX40 in the expansion and survival of CD4 T-cell-derived double-negative T cells.

Cell death & disease; 9(6) pg616

23 May 2018

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Walton, Z E

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.

Cell; 174(1) pg72-87.e32

28 Jun 2018

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mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3

Journal of immunology (Baltimore, Md. : 1950); 201(2) pg481-492

15 Jul 2018

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TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype.

Cell; 174(2) pg285-299.e12

12 Jul 2018

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Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis.

The Journal of Experimental Medicine; 215(7) pg1947-1963

2 Jul 2018

29899037
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A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide-Autoreactive CD4

Journal of immunology (Baltimore, Md. : 1950); 201(4) pg1194-1210

15 Aug 2018

29987163
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Jung, K B

Interleukin-2 induces the in vitro maturation of human pluripotent stem cell-derived intestinal organoids.

Nature Communications; 9(1) pg3039

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PD-1 Controls Follicular T Helper Cell Positioning and Function.

Immunity; 49(2) pg264-274.e4

21 Aug 2018

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Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy.

Journal of immunology (Baltimore, Md. : 1950); 201(7) pg2094-2106

1 Oct 2018

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IL-2-Anti-IL-2 Monoclonal Antibody Immune Complexes Inhibit Collagen-Induced Arthritis by Augmenting Regulatory T Cell Functions.

Journal of immunology (Baltimore, Md. : 1950); 201(7) pg1899-1906

1 Oct 2018

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Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation.

Cell death & disease; 9(9) pg890

30 Aug 2018

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PIP5 Kinases Regulate Membrane Phosphoinositide and Actin Composition for Targeted Granule Secretion by Cytotoxic Lymphocytes.

Immunity; 49(3) pg427-437.e4

18 Sep 2018

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USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein.

The Journal of Experimental Medicine; 215(11) pg2850-2867

5 Nov 2018

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Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution.

Immunity; 49(4) pg666-677.e6

16 Oct 2018

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Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens.

Cell; 175(4) pg1141-1155.e16

1 Nov 2018

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SUMOylation of ROR-Î³t inhibits IL-17 expression and inflammation via HDAC2.

Nature Communications; 9(1) pg4515

30 Oct 2018

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Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo.

Proceedings of the National Academy of Sciences of the United States of America; 115(46) pgE10907-E10914

13 Nov 2018

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VISTA expressed in tumour cells regulates T cell function.

British Journal of Cancer; 120(1) pg115-127

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An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis.

Immunity; 49(5) pg943-957.e9

20 Nov 2018

30389414
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Siddiqui, I

Intratumoral Tcf1

Immunity; 50(1) pg195-211.e10

15 Jan 2019

30635237
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Mowel, W K

Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA.

Immunity; 47(3) pg435-449.e8

19 Sep 2017

28930659
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Suárez-Fueyo, A

Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype.

Journal of immunology (Baltimore, Md. : 1950); 200(9) pg3077-3086

1 May 2018

29602774
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León-Ponte, M

Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor.

Blood; 109(8) pg3139-46

15 Apr 2007

17158224
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Martín, P

Characterization of a new subpopulation of mouse CD8alpha+ B220+ dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential.

Blood; 100(2) pg383-90

15 Jul 2002

12091326
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Åhsberg, J

Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.

The Journal of Biological Chemistry; 288(46) pg33449-61

15 Nov 2013

24078629
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Dépis, F

Unstable FoxP3+ T regulatory cells in NZW mice.

Proceedings of the National Academy of Sciences of the United States of America; 113(5) pg1345-50

2 Feb 2016

26768846
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Gérard, A

The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration.

Blood; 113(24) pg6138-47

11 Jun 2009

19139083
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Mostböck, S

IL-2/anti-IL-2 antibody complex enhances vaccine-mediated antigen-specific CD8+ T cell responses and increases the ratio of effector/memory CD8+ T cells to regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 180(7) pg5118-29

1 Apr 2008

18354238
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Pérol, L

Loss of immune tolerance to IL-2 in type 1 diabetes.

Nature Communications; 7 pg13027

6 Oct 2016

27708334
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Martín, P

Characterization of a new subpopulation of mouse CD8alpha+ B220+ dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential.

Blood; 100(2) pg383-90

15 Jul 2002

12091326
Show Usages

Åhsberg, J

Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.

The Journal of Biological Chemistry; 288(46) pg33449-61

15 Nov 2013

24078629
Show Usages

Dépis, F

Unstable FoxP3+ T regulatory cells in NZW mice.

Proceedings of the National Academy of Sciences of the United States of America; 113(5) pg1345-50

2 Feb 2016

26768846
Show Usages

Gérard, A

The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration.

Blood; 113(24) pg6138-47

11 Jun 2009

19139083
Show Usages

Mostböck, S

IL-2/anti-IL-2 antibody complex enhances vaccine-mediated antigen-specific CD8+ T cell responses and increases the ratio of effector/memory CD8+ T cells to regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 180(7) pg5118-29

1 Apr 2008

18354238
Show Usages

Suárez-Fueyo, A

Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype.

Journal of immunology (Baltimore, Md. : 1950); 200(9) pg3077-3086

1 May 2018

29602774
Show Usages

León-Ponte, M

Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor.

Blood; 109(8) pg3139-46

15 Apr 2007

17158224
Show Usages

Pérol, L

Loss of immune tolerance to IL-2 in type 1 diabetes.

Nature Communications; 7 pg13027

6 Oct 2016

27708334
Show Usages

Yang, L

Synergetic Functional Nanocomposites Enhance Immunotherapy in Solid Tumors by Remodeling the Immunoenvironment.

Advanced science (Weinheim, Baden-Wurttemberg, Germany); 6(8) pg1802012

16 Feb 2019

31016114
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Adoue, V

The Histone Methyltransferase SETDB1 Controls T Helper Cell Lineage Integrity by Repressing Endogenous Retroviruses.

Immunity; 50(3) pg629-644.e8

19 Mar 2019

30737147
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Niogret, C

Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.

Nature Communications; 10(1) pg1444

29 Mar 2019

30926899
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Srivastava, S

Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting.

Cancer Cell; 35(3) pg489-503.e8

18 Mar 2019

30889382
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Hu, M D

Epithelial IL-15 Is a Critical Regulator of γδ Intraepithelial Lymphocyte Motility within the Intestinal Mucosa.

Journal of immunology (Baltimore, Md. : 1950); 201(2) pg747-756

15 Jul 2018

29884699
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Lane, R S

IFNγ-activated dermal lymphatic vessels inhibit cytotoxic T cells in melanoma and inflamed skin.

The Journal of Experimental Medicine; 215(12) pg3057-3074

3 Dec 2018

30381467
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Yin, W

Single-cell RNA-Seq analysis identifies a noncoding

The Journal of Biological Chemistry; 294(1) pg290-298

4 Jan 2019

30404921
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Mathies, F

Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3

Journal of immunology (Baltimore, Md. : 1950); 201(12) pg3558-3568

15 Dec 2018

30446566
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Ren, W

Slc6a13 deficiency promotes Th17 responses during intestinal bacterial infection.

Mucosal Immunology; 12(2) pg531-544

0 Mar 2019

30523310
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Weckbach, L T

Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis.

The Journal of Experimental Medicine; 216(2) pg350-368

4 Feb 2019

30647120
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Davies, A J

Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury.

Cell; 176(4) pg716-728.e18

7 Feb 2019

30712871
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Pai, C S

Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.

Immunity; 50(2) pg477-492.e8

19 Feb 2019

30737146
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Yang, J

Baicalin ameliorates lupus autoimmunity by inhibiting differentiation of Tfh cells and inducing expansion of Tfr cells.

Cell death & disease; 10(2) pg140

13 Feb 2019

30760702
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Miyamoto, C

Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation.

Nature Communications; 10(1) pg447

25 Jan 2019

30683858
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van den Ham, H

Proteomic Profiling of Mouse Helper T Cell Differentiation.

Proteomics; 19(7) pge1800045

1 Apr 2019

30758134
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Sakai, Y

Distinct chemotherapy-associated anti-cancer immunity by myeloid cells inhibition in murine pancreatic cancer models.

Cancer Science; 110(3) pg903-912

1 Mar 2019

30657234
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van der Veeken, J

Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells.

Immunity; 50(5) pg1202-1217.e7

21 May 2019

31027997
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Komuczki, J

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β.

Immunity; 50(5) pg1289-1304.e6

21 May 2019

31079916
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Tuncel, J

T cell anergy in perinatal mice is promoted by T reg cells and prevented by IL-33.

The Journal of Experimental Medicine; 216(6) pg1328-1344

3 Jun 2019

30988052
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Kotov, J A

BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors.

The Journal of Experimental Medicine; 216(6) pg1450-1464

3 Jun 2019

31053612
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Zeleznjak, J

The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors.

The Journal of Experimental Medicine; 216(8) pg1809-1827

5 Aug 2019

31142589
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Growth Factors & Cytokines