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Growth Factors & Cytokines

Recombinant Murine IL-3

Product Details

Catalogue Number: 213-13
Description:

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages.  Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity.  Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles.  Many of the IL-3 activities depend upon co-stimulation with other cytokines.  IL-3 is a species-specific, variably glycosylated cytokine.  Recombinant Murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.

Source: E.coli

Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor

AA Sequence: MDTHRLTRTL NCSSIVKEII GKLPEPELKT DDEGPSLRNK SFRRVNLSKF VESQGEVDPE DRYVIKSNLQ KLNCCLPTSA NDSALPGVFI RDLDDFRKKL RFYMVHLNDL ETVLTSRPPQ PASGSVSPNR GTVEC

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.

Calculated Molecular Weight: 15.1 kDa

Accession Number: P01586

Gene ID: 16187

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

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Existing reviews
Better than any other brand
Used to treat cells but used different company products and they weren't got delivered it as fast as this one
From:  Cansu | Date:  7/28/2020
Recombinant Murine IL-3
We use this product to make stock dilutions, and store at -20. until we need to prep more murine media. They had always worked well post thaw
From:  Nichole | Date:  8/26/2020