Recombinant Murine IL-7 2 ReviewsSubmit a Review Product Details Catalog Number: 217-17 Description: IL-7 is a hematopoietic growth factor that primarily affects early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2. Human and murine IL-7 are cross-species reactive. Recombinant Murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues. Note: This item is currently on indefinite backorder. Synonyms: Lymphopoietin 1(LP-1), pre-B cell factor Source: E.coli AA Sequence: MECHIKDKEG KAYESVLMIS IDELDKMTGT DSNCPNNEPN FFRKHVCDDT KEAAFLNRAA RKLKQFLKMN ISEEFNVHLL TVSQGTQTLV NCTSKEEKNV KEQKKNDACF LKRLLREIKT CWNKILKGSI Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg. Calculated Molecular Weight: 15 kDa Accession Number: P10168 Gene ID: 16196 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Mouse, Mouse + Human References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell Cancer Immune System Inflammation Stem Cells & Differentiation Recent Citations First Author Ashby, J F Title Microfluidic T Cell Selection by Cellular Avidity. Citation Advanced Healthcare Materials; 11(16) pge2200169 PubMed ID 35657072 First Author Han, J Title Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity. Citation The Journal of Experimental Medicine; 219(6) PubMed ID 35532553 First Author Nayak, R C Title Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis. Citation Nature Communications; 13(1) pg3056 PubMed ID 35650206 Product Reviews Existing reviews Works everytime Happy to use this cytokine. Very efficient and economically priced. The product comes with all the relevant information and protocols on handling. Very helpful for expanding T cells and during ACT experiments. From: Vineet | Date: 8/10/2020 × Works everytime Happy to use this cytokine. Very efficient and economically priced. The product comes with all the relevant information and protocols on handling. Very helpful for expanding T cells and during ACT experiments. From: Vineet | Date: 8/10/2020 Close Great pro-survival cytokine for mouse T cells We routinely use this great cytokine to generate mouse memory CD8+ T cells and also keep naive T cells alive. The pricing and consistency of this cytokine can't be beat. From: Chirag | Date: 8/31/2020 × Great pro-survival cytokine for mouse T cells We routinely use this great cytokine to generate mouse memory CD8+ T cells and also keep naive T cells alive. The pricing and consistency of this cytokine can't be beat. From: Chirag | Date: 8/31/2020 Close
