KGF (FGF‐7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF‐7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF/FGF‐7 signals through FGFR 2b. KGF (FGF‐7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Murine KGF (FGF-7) is an 18.8 kDa protein consisting of 163 amino acid residues.
Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7
CNDMSPEQTA TSVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNSYNIMEIR TVAVGIVAIK GVESEYYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHSGG EMFVALNQKG IPVKGKKTKK EQKTAHFLPM AIT
≥ 95% by SDS-PAGE gel and HPLC analyses.
Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.5-5.0 ng/ml
Calculated Molecular Weight:
Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)
100μg is the largest vial size for this product.
Larger sizes supplied as multiple 50μg and/or 100μg vials.
Not for human use.