Animal-Free Recombinant Murine Leptin 0 ReviewsSubmit a Review Product Details Catalog Number: AF-450-31 Description: Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant Murine Leptin is a 16.2 kDa protein containing 147 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Obesity protein (OB) AA Sequence: MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Not available. Calculated Molecular Weight: 16.2 kDa Accession Number: P41160 Gene ID: 16846 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) Cross Reactivity Cited in References: Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Apoptosis Diabetes/Weight Regulation Immune System Inflammation Neurobiology Wound Healing Recent Citations First Author Andres-Hernando, A Title Umami-induced obesity and metabolic syndrome is mediated by nucleotide degradation and uric acid generation Citation Nature Metabolism; 3(9) pg1189-1201 PubMed ID 34552272
