Recombinant Murine MCP-5 (CCL12) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-04 Description: The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Murine MCP-5 is a 9.3 kDa protein containing 82 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Source: E.coli Synonyms: Monocyte Chemotactic Protein-5, CCL12 AA Sequence: GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-50.0 ng/ml. Calculated Molecular Weight: 9.3 kDa Accession Number: Q62401 Gene ID: 20293 crossreactivity: Bacteria, Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Cancer Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy product.subtitle.recentcitations First Author Sarafi, M N Title Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1. Citation The Journal of Experimental Medicine; 185(1) pg99-109 PubMed Id 8996246 First Author Sawada, S Title Disturbed CD4+ T cell homeostasis and in vitro HIV-1 susceptibility in transgenic mice expressing T cell line-tropic HIV-1 receptors. Citation The Journal of Experimental Medicine; 187(9) pg1439-49 PubMed Id 9565636 First Author Gilbert, L A Title DNA damage-mediated induction of a chemoresistant niche. Citation Cell; 143(3) pg355-66 PubMed Id 21029859