Recombinant Murine MIP-3α (CCL20) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-27 Description: MIP-3α is a CC chemokine, expressed in the liver, lymph nodes, appendix, PBL and lungs that can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells, and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant Murine MIP-3α is a 7.9 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Macrophage Inflammatory Protein-3α, CCL20, LARC, Exodus-1 AA Sequence: ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract murine CCR6-transfected HEK293 cells using a concentration range of 0.1-10.0 ng/ml Calculated Molecular Weight: 7.9 kDa Accession Number: O89093 Gene ID: 20297 crossreactivity: Human, Human + Mouse, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Röhrl, J Title Specific binding and chemotactic activity of mBD4 and its functional orthologue hBD2 to CCR6-expressing cells. Citation The Journal of Biological Chemistry; 285(10) pg7028-34 PubMed Id 20068036 First Author Li, J Title Deficiency of β-arrestin1 ameliorates collagen-induced arthritis with impaired TH17 cell differentiation. Citation Proceedings of the National Academy of Sciences of the United States of America; 110(18) pg7395-400 PubMed Id 23589893 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871
