Recombinant Rat SDF-1β (CXCL12) 0 ReviewsSubmit a Review Product Details Catalog Number: 400-32B Description: SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1β protein, produced by an N-terminal truncation of two additional amino acids, after removal of the signal sequence, contains 72 amino acid residues. Recombinant Rat SDF-1β is an 8.4 kDa protein containing 72 amino acid residues. Source: E.coli Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF AA Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: Q9QZD1 Gene ID: 24772 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Chemotaxis Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Recent Citations First Author Bakondi, B Title Multimodal Delivery of Isogenic Mesenchymal Stem Cells Yields Synergistic Protection from Retinal Degeneration and Vision Loss Citation Stem Cells Translational Medicine; 6(2) pg444-457 PubMed ID 28191768 First Author Chen, D Title Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration. Citation Scientific Reports; 5 pg16813 PubMed ID 26578388
