Small Molecules

Biogems

U0126

Product Details

Catalog Number: 1095821
Description:

U0126 is a highly selective inhibitor of MEK1 (IC50 of 72nM) and MEK2 (IC50 of 58nM) that antagonizes AP-1 transcriptional activity. U0216 helps maintain human pluripotent stem cells in the undifferentiated state. It is also reported to sensitize cells to anoikis, as upon treatment with U0126 cells deprived of anchorage enter apoptosis.

Synonyms: U-0126, UO-126

Application:

Formulation:
Crystalline solid
Chemical Name:
(2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanylmethylidene]butanedinitrile
Molecular Formula:

C18H16N6S2

Molecular Weight:
380.5
CAS Number:
109511-58-2
Purity:
≥98%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.