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Monoclonal Antibodies

Biogems

Anti-Human CD4 Purified (Clone#: RPA-T4)

Detalles del Producto

Nùmero de Catalogo 06121-20
Descripcion
The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.

Source: Isotype: Mouse IgG1, kappa; Clone#: RPA-T4

Note:

Product supplied by Biogems

crossreactivity: Research Interest

Country Of Origin: USA

Not for human use.