Anti-Mouse CD70 SAFIRE Purified (Clone#: FR70) Product Details Catalogue Number: 02812-25 Description: The FR70 monoclonal antibody specifically binds to mouse CD70, a 30-33 kDA type II transmembrane protein and member of the TNF superfamily. CD70 is the ligand for CD27 and is expressed on dendritic cells, activated B cell, and a subset of activated T cells at lower levels. Its main role is in regulating B cell activation and immunoglobulin synthesis. CD70 expressing cells are able to co-stimulate T cell proliferation and upregulate cytokine production. The FR70 antibody is reported to block the binding of CD70 to CD27. Source: Isotype: Rat IgG2b, kappa; Clone#: FR70 Note: Product supplied by BiogemsSAFIRE (Sodium Azide Free Immensely Reduced Endotoxin) products are BioGems’ line of functional antibodies that can be used for activation, blocking, and neutralization studies. They are manufactured carrier and sodium azide free, with immensely reduced endotoxin levels of 0.01 EU/ug or lower for in vivo and in vitro applications. crossreactivity: Mouse Country Of Origin: USA Not for human use. CoA Search Product Line Research Interest Immune System
