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Monoclonal Antibodies

Biogems

Anti-Mouse IL-1 alpha SAFIRE Purified (Clone#: ALF-161)

Detalles del Producto

Nùmero de Catalogo 82312-25
Descripcion
IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. The ALF-161 monoclonal antibody reacts with the precursor, secreted and membrane-associated forms of mouse IL-1 α. The antibody is reported to be usable as the capture antibody in an ELISA assay and exhibits neutralization properties.

Source: Isotype: Armenian Hamster IgG; Clone#: ALF-161

Note:

Product supplied by Biogems

SAFIRE (Sodium Azide Free Immensely Reduced Endotoxin) products are BioGems’ line of functional antibodies that can be used for activation, blocking, and neutralization studies. They are manufactured carrier and sodium azide free, with immensely reduced endotoxin levels of 0.01 EU/ug or lower for in vivo and in vitro applications.

crossreactivity: Research Interest

Country Of Origin: USA

Not for human use.