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Pre-Coated ELISA Kits

Biogems

Human TLR-3 Pre-Coated ELISA Kit

Detalles del Producto

Nùmero de Catalogo BGK6Y0F1
Descripcion

TLR-3 is a single-pass type I receptor that binds to and signals the presence of microbial pathogens and double stranded RNA (dsRNA) viruses. Signaling through TLR-3 can promote the NF-κB pathway to initiate innate and adaptive immune responses to bacterial and viral infections, as well as the p53 pathway to trigger apoptosis in cells infected with dsRNA viruses. TLR-3 belongs to a family of structurally-related toll-like receptors (TLRs) containing an N-terminal domain rich in leucine repeats, and a C-terminal intracellular Toll/interleukin (IL)-1 (TIL) domain. TLR-3 is expressed primarily in dendritic cells of the placenta and pancreas where it can reside on both sides of the plasma membrane, and in the endosomal compartment of the cells. The BioGems Human TLR-3 Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure TLR-3 with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for TLR-3. It contains NS0-expressed recombinant TLR-3. The detection antibody is a biotinylated goat polyclonal antibody specific for TLR-3. The kit is analytically validated with ready to use reagents.

Sandwich ELISA:

Assay Type:
Solid Phase Sandwich ELISA: 96-Well Strip Plate
Sensitivity:
<10 pg/ml 
Range:
156pg/ml-10,000pg/ml
Specificity:
Natural and recombinant Human TLR-3
Uniprot:
E6Y0F1
Interference:
No detectable cross-reactivity with other relevant proteins

Note:

Product supplied by Biogems

Country Of Origin: USA

Not for human use.