Small Molecules

Biogems

LY2157299

Detalles del Producto

Nùmero de Catalogo 7007224
Descripcion

LY2157299 is a potent inhibitor of Transforming Growth factor-Beta Receptor I (TGF-BetaR). TGF-Beta1 is involved in the control of cell growth, proliferation, differentiation, and apoptosis. LY2157299 is reported to disrupt Smad-2 phosphorylation in Human Umbilical Vein Endothelial Cells (HUVEC) and inhibit the growth and migration of tumor cells.

Synonyms: LY 2157299, LY-2157299, Galunisertib

Application:

Formulation:
Crystalline solid
Chemical Name:
4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide
Molecular Formula:

C22H19N5O

Molecular Weight:
369.4
CAS Number:
700874-72-2
Purity:
≥98%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.