Murine CD40 Ligand Pre-Coated ELISA Kit Detalles del Producto Nùmero de Catalogo BGK27548 Descripcion CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anCHOred CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to ""immunodeficiency with hyper-IgM"", a disease characterized by failure to produce IgG, IgA and IgE. The BioGems Murine CD40 Ligand Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure CD40 Ligand with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for CD40 Ligand. It contains NS0-expressed recombinant CD40 Ligand. The detection antibody is a biotinylated goat polyclonal antibody specific for CD40 Ligand. The kit is analytically validated with ready to use reagents Sandwich ELISA: Assay Type: Solid Phase Sandwich ELISA: 96-Well Strip Plate Sensitivity: <10 pg/ml Range: 62.5pg/ml-4000pg/ml Specificity: Natural and recombinant Murine CD40 Ligand Uniprot: P27548 Interference: No detectable cross-reactivity with other relevant proteins Note: Product supplied by Biogems Product Line Country Of Origin: USA Not for human use.