NU 7441 Product Details Catalogue Number: 5039598 Description: NU 7441 is a selective and potent DNA-PK inhibitor (IC50 14nM) and P13K inhibitor (IC50 5uM). It is reported enhance the cytotoxic effects of radiation in cancer cell lines and potentiate the effects of etoposide and doxorubicin. NU 7441 is also reported to enhance the efficiency of CRISPR-Cas9 mediated homology-directed repair (HDR) 2 to 4 fold and decrease nonhomologous end-joining (NHEJ) frequency by 2 fold. Synonyms: KU57788, KU 57788, NU-7441, NU7441 Application: Formulation: Crystalline solid Chemical Name: 8-dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one Molecular Formula: C25H19NO3S Molecular Weight: 413.5 CAS Number: 503468-95-9 Purity: ≥98% Note: Product supplied by Biogems Country Of Origin: USA Not for human use. CoA Search Product Line Research Interest Cancer
