Small Molecules

Biogems

Rapamycin

Detalles del Producto

Nùmero de Catalogo 5318893
Descripcion

Rapamycin was first evaluated as an antifungal agent, but is now studied for its potent immunosuppressive and antiproliferative properties. It forms a complex with FKBP12 and directly binds to mTORC1, inhibiting the functions of the mTOR pathway. Rapamycin is reported to block protein synthesis, arrest cell cycle progression, and inhibit IL-2 signal transduction mechanisms.

Synonyms: Sirolimus, Rapamune, AY 22989

Application:

Formulation:
Crystalline solid
Chemical Name:
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)­9,10,12,13,14,21,22,23,24,25,26,27,32,33,34, 34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2­[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy­6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4] oxaazacyclohentriacontine­1,5,11,28,29 (4H,6H,31H)-pentone
Molecular Formula:

C51H79NO13

Molecular Weight:
914.2
CAS Number:
53123-88-9
Purity:
≥95%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.