Chemokines

Recombinant Human BRAK (CXCL14)

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Product Details

Catalogue Number: 300-50
Description:

Breast and Kidney-expressed chemokine (BRAK) is a CXC chemokine expressed in normal tissue in the absence of inflammatory stimuli, and infrequently expressed in cancer cell lines. BRAK is known to be a highly selective monocyte chemoattractant. However, main function and receptor selectivity is unknown at this time. BRAK contains the four highly conserved cysteine residues present in CXC chemokines. The sequence of the mature protein consists of 87 amino acid residues, and is approximately 30% homologous to the sequences of MIP-2 α and β. Recombinant Human BRAK is a 9.4 kDa protein containing 77 amino acid residues.

Source: E.coli

Synonyms: Breast and Kidney-expressed chemokine, CXCL14, bolekine, NJAC

AA Sequence: SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract activated monocytes using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 9.4 kDa

Accession Number: O95715

Gene ID: 9547

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Zeng, J
Title
Chemokine CXCL14 is associated with prognosis in patients with colorectal carcinoma after curative resection.
Citation
Journal of Translational Medicine; 11 pg6
PubMed Id
First Author
Singh, K
Title
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Citation
Scientific Reports; 7(1) pg4267
PubMed Id
First Author
Suzuki, H
Title
CXCL14-like Immunoreactivity Exists in Somatostatin-containing Endocrine Cells, and in the Lamina Propria and Submucosal Somatostatinergic Nervous System of Mouse Alimentary Tract.
Citation
Acta Histochemica et Cytochemica; 50(6) pg149-158
PubMed Id