Recombinant Human ENA-78 (CXCL5) (5-78 a.a.) 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 300-22 Descripcion ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokines that bind to the CXCR1 and CXCR2 receptors. Recombinant Human ENA-78 is an 8.0 kDa protein consisting of 74 amino acid residues. Source: E.coli Synonyms: Epithelial Neutrophil Activating Peptide-78, CXCL5 AA Sequence: AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKEN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration of 5.0-10.0 ng/ml. Calculated Molecular Weight: 8 kDa Accession Number: P42830 Gene ID: 6374 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Hamster, Human, Mouse References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations Primer autor Du, Y Titulo Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. Citar The Journal of Experimental Medicine; 219(7) PudMed id 35640018 Primer autor Li, Q Titulo mRNA-engineered mesenchymal stromal cells expressing CXCR2 enhances cell migration and improves recovery in IBD. Citar Molecular therapy. Nucleic acids; 26 pg222-236 PudMed id 34513306 Primer autor Fonseca, K L Titulo Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils Citar Mucosal Immunology; 13(5) pg836-848 PudMed id 32203062