Chemokines

Recombinant Human Exodus-2 (CCL21)

Detalles del Producto

Nùmero de Catalogo 300-35
Descripcion

Exodus-2 is a CC chemokine that signals through the CCR7 receptor. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant Human Exodus-2 is a 12.2 kDa protein containing 111 amino acid residues.

Note: On December 30, 2019 this protein will be discontinued, and replaced with (PeproTech catalog# 300-35A)

Expressed using different clones, Cat# 300-35 and Cat# 300-35A differ from one another at amino acid positions 100 and 101, where the amino acids arginine (R) and lysine (K) are transposed.

Source: E.coli

Synonyms: CCL21, 6Ckine, SLC

AA Sequence: SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG P

Biological Activity: Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10.0-100.0 ng/ml.

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Calculated Molecular Weight: 12.2 kDa

Accession Number: O00585

Gene ID: 6366

Cross Reactivity:
Bacteria, Human , Human + Mouse, Leech, Monkey, Mouse, Pig
Research Interest

Country Of Origin: USA

Not for human use.