Exodus‐2 is a CC chemokine that signals through the CCR7 receptor. It is expressed in lymphatic endothelial cells, the spleen and appendix. Exodus‐2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus‐2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant Human Exodus‐2 (CCL21) is a 12.2 kDa protein containing 111 amino acid residues.*Human Exodus-2 (Catalog Number 300-35A) has replaced Human Exodus-2 (Catalog Number 300-35)
SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P
≥ 98% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2.
Calculated Molecular Weight:
Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)
Not for human use.