Recombinant Human FGF-17 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 100-27 Descripcion FGF-17 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-17 signals through FGFR 1c, 2c, 3c, and 4. FGF-17 promotes the induction and patterning of brain development during embryogenesis. Recombinant Human FGF-17 is a 22.7 kDa protein consisting of 195 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-17, FGFH AA Sequence: MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg. Calculated Molecular Weight: 22.7 kDa Accession Number: O60258 Gene ID: 8822 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 250μg is the largest vial size for this product. Larger sizes supplied as multiple 250μg vials. crossreactivity: Human, Mouse, Rat References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations Primer autor Cinque, L Titulo MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. Citar The EMBO Journal; pge105696 PudMed id 32716134 Primer autor Savchenko, E Titulo FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes. Citar Scientific Reports; 9(1) pg9610 PudMed id 31270389 Primer autor Westphal, S Titulo Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Citar Scientific Reports; 9(1) pg8470 PudMed id 31186471