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Animal-Free Cytokines

Animal-Free Recombinant Human FGF-basic (146 a.a.)

Detalles del Producto

Nùmero de Catalogo AF-100-18C
Descripcion
Animal-Free Recombinant Human FGF-basic (146 a.a.)

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic (146 a.a.) is a 16.4 kDa protein consisting of 146 amino acid residues.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

AA Sequence: PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.

Animal-Free Recombinant Human FGF-basic (146 a.a.) Biological Activity Graph

Calculated Molecular Weight: 16.4 kDa

Accession Number: P09038

Gene ID: 2247

Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

Primer autor
Tang, Q
Titulo
Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion
Citar
Cell Death & Disease; 12(10) pg854
PudMed id
Primer autor
Gupta, B
Titulo
The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus.
Citar
Cell Reports; 36(8) pg109588
PudMed id
Primer autor
Zhu, T
Titulo
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Citar
Cell Death Discovery; 7(1) pg126
PudMed id

product.subtitle.productreviews

Comentarios existentes
FGF Basic for for Organoid Culture
Used FGF-2 for Head and Neck squamous Cell Carcinoma Organoid Culture.
Quick Overnight Delivery is great.
Works great for organoid culture.
De:  Hardik | Fecha:  31/08/2020