Animal-Free Recombinant Human G-CSF 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo AF-300-23 Descripcion G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant Human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFβ, pluripoietin AA Sequence: TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to stimulate the proliferation of mouse NFS-60 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 18.7 kDa Accession Number: P09919 Gene ID: 1440 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Mouse, Plant References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Angiogenesis/Cardiovascular Cancer Diabetes/Weight Regulation Immune System Inflammation Stem Cells & Differentiation product.subtitle.recentcitations Primer autor Murthy, S Titulo Danger signal extracellular calcium initiates differentiation of monocytes into SPP1/osteopontin-producing macrophages. Citar Cell death & disease; 13(1) pg53 PudMed id 35022393 Primer autor Thomé, C H Titulo NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia Citar Scientific Reports; 10(1) pg10315 PudMed id 32587277 Primer autor Xu, Y Titulo TAF1 plays a critical role in AML1-ETO driven leukemogenesis. Citar Nature Communications; 10(1) pg4925 PudMed id 31664040