Recombinant Human GCP-2 (CXCL6) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-41 Description: CXCL6, also known as GCP-2 in humans, is a connective tissue-derived CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. Human GCP-2, which is cross-reactive with murine cells, selectively attracts neutrophils, and has also been shown to exert anti-angiogenic activity. Recombinant Human GCP-2 is a 7.9 kDa protein containing 72 amino acid residues. Source: E.coli Synonyms: Granulocyte Chemotactic Protein-2, CXCL6, LIX (murine) AA Sequence: VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml. Calculated Molecular Weight: 7.9 kDa Accession Number: P80162 Gene ID: 6372 Note: 1mg will be provided as 2x500μg. crossreactivity: Bacteria, Hamster, Human, Monkey, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations First Author Rosenkilde, M M Title The CXC chemokine receptor encoded by herpesvirus saimiri, ECRF3, shows ligand-regulated signaling through Gi, Gq, and G12/13 proteins but constitutive signaling only through Gi and G12/13 proteins. Citation The Journal of Biological Chemistry; 279(31) pg32524-33 PubMed Id 15155729 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871 First Author Waldhoer, M Title The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis. Citation The Journal of Biological Chemistry; 278(21) pg19473-82 PubMed Id 12646575