Recombinant Human GRO-γ (CXCL3) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-40 Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Human GRO-γ is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. Source: E.coli Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSA γ), CXCL3, MIP-2β, GRO3 AA Sequence: ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/ml. Calculated Molecular Weight: 7.9 kDa Accession Number: P19876 Gene ID: 2921 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Hamster, Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing product.subtitle.recentcitations First Author Lee, A W Title A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citation The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed Id 31167786 First Author Alenazi, Y Title Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Citation Scientific Reports; 8(1) pg6333 PubMed Id 29679010 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871
