Recombinant Human IL-2 7 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 200-02 Descripcion IL-2 is a powerful immunoregulatory lymphokine produced by T cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond. Source: E.coli Synonyms: Interleukin-2, T-cell growth factor (TCGF), Aldesleukin AA Sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 15.5 kDa Accession Number: P60568 Gene ID: 3558 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Chicken, Cow, Cow + Mouse, Dog, Human, Human + Hamster, Human + Mouse, Human + Virus, Monkey, Mouse, Rat References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell COVID-19 AIDS/HIV Cancer Cell Culture Diabetes/Weight Regulation Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Allergy Transplantation product.subtitle.recentcitations Primer autor Ma, Y Titulo Identification and assessment of TCR-T cells targeting an epitope conserved in SARS-CoV-2 variants for the treatment of COVID-19. Citar International Immunopharmacology; 112 pg109283 PudMed id 36201943 Primer autor Karagiannis, F Titulo Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19. Citar Nature; 609(7928) pg801-807 PudMed id 35901960 Primer autor Wang, W Titulo Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors. Citar Advanced science (Weinheim, Baden-Wurttemberg, Germany); 9(22) pge2105810 PudMed id 35665491 product.subtitle.productreviews Comentarios existentes Excellent for Treg culture Very good for culture of human sorted Tregs, consistent across lots and vials. De: Julian | Fecha: 10/07/2020 × Excellent for Treg culture Very good for culture of human sorted Tregs, consistent across lots and vials. De: Julian | Fecha: 10/07/2020 Close hIL-2 Great product, works well to stimulate primary human T cells (tested for up to 2 weeks in culture). De: Kimberly | Fecha: 10/08/2020 × hIL-2 Great product, works well to stimulate primary human T cells (tested for up to 2 weeks in culture). De: Kimberly | Fecha: 10/08/2020 Close T cell culture Used in culturing primary human T cells - works great! De: Elizabeth | Fecha: 26/08/2020 × T cell culture Used in culturing primary human T cells - works great! De: Elizabeth | Fecha: 26/08/2020 Close hIL2 Very good product for culturing T cells in vitro. Works great. De: Kevin | Fecha: 26/08/2020 × hIL2 Very good product for culturing T cells in vitro. Works great. De: Kevin | Fecha: 26/08/2020 Close Primary T cells Worked well in expanding activated primary T cells. Customer service was great when I wanted to know its equivalent IU values. De: Adam | Fecha: 27/08/2020 × Primary T cells Worked well in expanding activated primary T cells. Customer service was great when I wanted to know its equivalent IU values. De: Adam | Fecha: 27/08/2020 Close Works just fine Aliquoted as recommended and worked just fine for several months. De: Tanja | Fecha: 27/08/2020 × Works just fine Aliquoted as recommended and worked just fine for several months. De: Tanja | Fecha: 27/08/2020 Close Primary T cell culture Worked well for culturing human CD4 and CD8 T cells. De: Michael | Fecha: 29/06/2023 × Primary T cell culture Worked well for culturing human CD4 and CD8 T cells. De: Michael | Fecha: 29/06/2023 Close
