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Growth Factors & Cytokines

Recombinant Human IL-2

Detalles del Producto

Nùmero de Catalogo 200-02
Descripcion

IL-2 is a powerful immunoregulatory lymphokine produced by T cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Source: E.coli

Synonyms: Interleukin-2, T-cell growth factor (TCGF), Aldesleukin

AA Sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

Calculated Molecular Weight: 15.5 kDa

Accession Number: P60568

Gene ID: 3558

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

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Comentarios existentes
Excellent for Treg culture
Very good for culture of human sorted Tregs, consistent across lots and vials.
De:  Julian | Fecha:  10/07/2020
hIL-2
Great product, works well to stimulate primary human T cells (tested for up to 2 weeks in culture).
De:  Kimberly | Fecha:  10/08/2020
T cell culture
Used in culturing primary human T cells - works great!
De:  Elizabeth | Fecha:  26/08/2020
hIL2
Very good product for culturing T cells in vitro. Works great.
De:  Kevin | Fecha:  26/08/2020
Primary T cells
Worked well in expanding activated primary T cells. Customer service was great when I wanted to know its equivalent IU values.
De:  Adam | Fecha:  27/08/2020
Works just fine
Aliquoted as recommended and worked just fine for several months.
De:  Tanja | Fecha:  27/08/2020