Animal-Free Recombinant Human IL-3 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo AF-200-03 Descripcion IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Interleukin-3, MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor AA Sequence: APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. Calculated Molecular Weight: 15 kDa Accession Number: P08700 Gene ID: 3562 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Human + Mouse, Monkey, Mouse References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Cancer Cell Culture Diabetes/Weight Regulation Immune System Stem Cells & Differentiation product.subtitle.recentcitations Primer autor Chen, W Titulo Reprogramming of human peripheral blood mononuclear cells into induced mesenchymal stromal cells using non-integrating vectors. Citar Communications Biology; 6(1) pg393 PudMed id 37041280 Primer autor Eernstman, J Titulo Novel variants in Krueppel like factor 1 that cause persistence of fetal hemoglobin in In(Lu) individuals Citar Scientific Reports; 11(1) pg18557 PudMed id 34535703 Primer autor Thornton, N Titulo Disruption of the tumour-associated EMP3 enhances erythrid proliferation and causes the MAM-negative phenotype Citar Nature Communications; 11(1) pg3569 PudMed id 32678083
