Animal-Free Recombinant Human IL-8 (CXCL8) (72 a.a.) 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo AF-200-08M Descripcion IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1 AA Sequence: SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: P10145 Gene ID: 3576 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Bacteria, Human, Mouse References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Apoptosis Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy Transplantation product.subtitle.recentcitations Primer autor Whittall, C Titulo A chemokine self-presentation mechanism involving formation of endothelial surface microstructures. Citar Journal of immunology (Baltimore, Md. : 1950); 190(4) pg1725-36 PudMed id 23325889 Primer autor Madenspacher, J H Titulo Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity. Citar The Journal of Biological Chemistry; 287(52) pg43730-40 PudMed id 23118226 Primer autor Raghuwanshi, S K Titulo The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions. Citar Journal of immunology (Baltimore, Md. : 1950); 189(6) pg2824-32 PudMed id 22869904
