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Chemokines

Recombinant Human Lymphotactin (XCL1)

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Detalles del Producto

Nùmero de Catalogo 300-20
Descripcion
Recombinant Human Lymphotactin (XCL1)

Lymphotactin is the only known member of the C chemokine family, and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes, but not towards monocytes or neutrophils. Recombinant Human Lymphotactin is a 10.0 kDa protein consisting of 92 amino acid residues.

Source: E.coli

Synonyms: XCL-1, SCM-1a, ATAC

AA Sequence: GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to bind α9 integrin expressed on the surface of MOLT4 cells.

Calculated Molecular Weight: 10 kDa

Accession Number: P47992

Gene ID: 6375

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

Primer autor
Abdullah Zubir, A Z
Titulo
The chemokine lymphotactin and its recombinant variants in oral cancer cell regulation
Citar
Oral Diseases;
PudMed id
Primer autor
Buskermolen, J K
Titulo
Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets.
Citar
Journal of Cellular Physiology; 232(11) pg2996-3005
PudMed id
Primer autor
Matsumoto, N
Titulo
A Novel α9 Integrin Ligand, XCL1/Lymphotactin, Is Involved in the Development of Murine Models of Autoimmune Diseases.
Citar
Journal of immunology (Baltimore, Md. : 1950); 199(1) pg82-90
PudMed id