Chemokines

Recombinant Human MEC (CCL28)

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Product Details

Catalogue Number: 300-57
Description:
Recombinant Human MEC (CCL28)

MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor, and chemoattracts resting CD4, CD8T-cells and eosinophils. MEC contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines. Recombinant Human MEC is a 12.3 kDa protein containing 108 amino acid residues.

Source: E.coli

Synonyms: Mucosae-associated Epithelial Chemokine, CCL28, CCK-1

AA Sequence: SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 12.3 kDa

Accession Number: Q9NRJ3

Gene ID: 56477

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Fu, Y
Title
CD27-CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression.
Citation
Cell Reports; 36(2) pg109344
PubMed Id
First Author
Park, J
Title
CCL28-induced RARβ expression inhibits oral squamous cell carcinoma bone invasion.
Citation
The Journal of Clinical Investigation; 129(12) pg5381-5399
PubMed Id
First Author
Buskermolen, J K
Title
Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets.
Citation
Journal of Cellular Physiology; 232(11) pg2996-3005
PubMed Id