Recombinant Human MEC (CCL28) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-57 Description: MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor, and chemoattracts resting CD4, CD8T-cells and eosinophils. MEC contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines. Recombinant Human MEC is a 12.3 kDa protein containing 108 amino acid residues. Source: E.coli Synonyms: Mucosae-associated Epithelial Chemokine, CCL28, CCK-1 AA Sequence: SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 12.3 kDa Accession Number: Q9NRJ3 Gene ID: 56477 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Fu, Y Title CD27-CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression. Citation Cell Reports; 36(2) pg109344 PubMed Id 34260905 First Author Park, J Title CCL28-induced RARβ expression inhibits oral squamous cell carcinoma bone invasion. Citation The Journal of Clinical Investigation; 129(12) pg5381-5399 PubMed Id 31487270 First Author Buskermolen, J K Title Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets. Citation Journal of Cellular Physiology; 232(11) pg2996-3005 PubMed Id 28387445
