Recombinant Human MEC (CCL28) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-57 Description: MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor, and chemoattracts resting CD4, CD8T-cells and eosinophils. MEC contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines. Recombinant Human MEC is a 12.3 kDa protein containing 108 amino acid residues. Source: E.coli Synonyms: Mucosae-associated Epithelial Chemokine, CCL28, CCK-1 AA Sequence: SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 12.3 kDa Accession Number: Q9NRJ3 Gene ID: 56477 crossreactivity: Bacteria, Human References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Karlsson, C Title Identification of the chemokine CCL28 as a growth and survival factor for human hematopoietic stem and progenitor cells. Citation Blood; 121(19) pg3838-42, S1-15 PubMed Id 23509159 First Author Mei, H E Title Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab. Citation Blood; 116(24) pg5181-90 PubMed Id 20829370 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871
