Recombinant Human Nesfatin-1 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 300-67 Descripcion Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Originally identified as a hypothalamic neuropeptide, nesfatin-1 is also expressed in other areas of the brain, in pancreatic islets β-cells, gastric endocrine cells, and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Recombinant Human Nesfatin-1 is a 9.7 kDa protein containing 82 amino acid residues. Source: E.coli Synonyms: None AA Sequence: VPIDIDKTKV QNIHPVESAK IEPPDTGLYY DEYLKQVIDV LETDKHFREK LQKADIEEIK SGRLSKELDL VSHHVRTKLD EL Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by an in vivo assay using healthy wild type male mice (C57BL/6J). Mice were treated via intraperitoneal injection once at a dose of 4µg Nesfatin-1/gm of body weight. Significant effects on body weight and food consumption were observed relative to saline-treated controls. Calculated Molecular Weight: 9.7 kDa Accession Number: P80303 Gene ID: 4925 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 100μg is the largest vial size for this product. Larger sizes supplied as multiple 100μg vials. PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest Diabetes/Weight Regulation Neurobiology
