Growth Factors & Cytokines

Recombinant Human PlGF-1

0 ReviewsSubmit a Review

Product Details

Catalogue Number: 100-06
Description:
Recombinant Human PlGF-1

PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, the colon, and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. Recombinant Human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 132 amino acid polypeptide chains.

Source: E.coli

Synonyms: Placenta Growth Factor-1, PlGF, PGF

AA Sequence (monomer): MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human monocytes of using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 29.7 kDa

Accession Number: P49763

Gene ID: 5228

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Lechertier, T
Title
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Citation
Nature Communications; 11(1) pg2810
PubMed Id
First Author
Kojovic, D
Title
Role of Elevated SFLT-1 on the Regulation of Placental Transporters in Women With Pre-Eclampsia.
Citation
Clinical And Translational Science; 13(3) pg580-588
PubMed Id
First Author
Ishihara, J
Title
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Citation
Nature Communications; 9(1) pg2163
PubMed Id