Chemokines

Recombinant Human TECK (CCL25)

Product Details

Catalogue Number: 300-45
Description:

TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells. Recombinant Human TECK is a 14.2 kDa protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Thymus Expressed Chemokine

AA Sequence: QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSKRNVSLL ISANSGL

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to bind CCR9 receptor expressed on the surface of MOLT4 cells.

Calculated Molecular Weight: 14.2 kDa

Accession Number: O15444

Gene ID: 6370

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Pabbisetty, S K
Title
Peripheral tolerance can be modified by altering KLF2-regulated Treg migration.
Citation
Proceedings of the National Academy of Sciences of the United States of America; 113(32) pgE4662-70
PubMed Id
First Author
Watts, A O
Title
β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR.
Citation
The Journal of Biological Chemistry; 288(10) pg7169-81
PubMed Id
First Author
Kunkel, E J
Title
Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity.
Citation
The Journal of Experimental Medicine; 192(5) pg761-8
PubMed Id

product.subtitle.productreviews

Existing reviews
works as expected
Our lab appreciates the fast delivery, careful packaging and products quality. We purchase cytokines regularly and this one to works as expected. High quality and reliable for consistent results.
From:  Ioana | Date:  26/08/2020