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Chemokines

Recombinant Murine BCA-1/BLC (CXCL13)

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Detalles del Producto

Nùmero de Catalogo 250-24
Descripcion
Recombinant Murine BCA-1/BLC (CXCL13)

BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor, CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes, and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Murine BLC is a 9.8 kDa protein containing 88 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

Source: E.coli

Synonyms: B cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand

AA Sequence: ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human B cells.

Recombinant Murine BCA-1/BLC (CXCL13) Biological Activity Graph

Calculated Molecular Weight: 9.8 kDa

Accession Number: O55038

Gene ID: 55985

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

Primer autor
Ma, L
Titulo
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
Citar
The Journal of Experimental Medicine; 218(12)
PudMed id
Primer autor
Cruz-Zárate, D
Titulo
Myo1g is required for efficient adhesion and migration of activated B lymphocytes to inguinal lymph nodes
Citar
Scientific Reports; 11(1) pg7197
PudMed id
Primer autor
Shi, J
Titulo
PD-1 Controls Follicular T Helper Cell Positioning and Function.
Citar
Immunity; 49(2) pg264-274.e4
PudMed id