Recombinant Murine C10 (CCL6) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-06 Description: Murine C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues. Recombinant Murine C10 is a 10.7 kDa protein containing 95 amino acid residues. Source: E.coli Synonyms: CCL6, MRP-1 AA Sequence: GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract Balb/c mouse spleen MNCs using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 10.7 kDa Accession Number: P27784 Gene ID: 20305 crossreactivity: Bacteria, Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Núñez, V Title Retinoid X receptor alpha controls innate inflammatory responses through the up-regulation of chemokine expression. Citation Proceedings of the National Academy of Sciences of the United States of America; 107(23) pg10626-31 PubMed Id 20498053 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871 First Author Krishnan, V Title Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1 Citation Communications Biology; 3(1) pg524 PubMed Id 32963283
