Recombinant Murine Exodus-2 (CCL21) 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 250-13 Descripcion Exodus-2 is a CC chemokine that can signal through the CCR7 receptor. It is expressed in lymphatic endothelial cells, the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant Murine Exodus-2 is a 12.0 kDa protein containing 110 amino acid residues. Source: E.coli Synonyms: CCL21, 6Ckine, SLC AA Sequence: SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 12 kDa Accession Number: P86793 Gene ID: 65956 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. crossreactivity: Bacteria, Human, Human + Mouse, Leech, Monkey, Mouse, Rat References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations Primer autor Chang, M H Titulo Arthritis flares mediated by tissue-resident memory T cells in the joint. Citar Cell Reports; 37(4) pg109902 PudMed id 34706228 Primer autor Arasa, J Titulo Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation. Citar The Journal of Experimental Medicine; 218(7) PudMed id 33988714 Primer autor Riegel, K Titulo RAF kinases are stabilized and required for dendritic cell differentiation and function Citar Cell Death and Differentiation; 27(4) pg1300-1315 PudMed id 31541179