Animal-Free Recombinant Murine GM-CSF 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo AF-315-03 Descripcion GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α AA Sequence: MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 14.2 kDa Accession Number: P01587 Gene ID: 12981 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Mouse, Rat, Trout References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Cancer Cell Culture Immune System Inflammation Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations Primer autor Tu, Q Titulo Mitochondrial DNA mediates immunoparalysis of dendritic cells in sepsis via STING signalling. Citar Cell Proliferation; 55(12) pge13328 PudMed id 36106559 Primer autor Consonni, M Titulo Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia Citar Nature Communications; 12(1) pg4844 PudMed id 34381053 Primer autor Gong, X Titulo A smart multiantenna gene theranostic system based on the programmed assembly of hypoxia-related siRNAs Citar Nature Communications; 12(1) pg3953 PudMed id 34172725