Recombinant Murine I-TAC (CXCL11) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-29 Description: I-TAC is a "non-ELR" CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2-activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, or monocytes. Recombinant Murine I-TAC is a 9.0 kDa protein containing 79 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines. Source: E.coli Synonyms: Interferon Inducible T-Cell α Chemokine, CXCL11, B-R1 AA Sequence: FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRRQNM Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract murine CXCR3-transfected HEK293 cells using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 9 kDa Accession Number: Q9JHH5 Gene ID: 56066 crossreactivity: Bacteria, Human, Monkey, Mouse, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author He, H Title Aging-induced IL27Ra signaling impairs hematopoietic stem cells. Citation Blood; 136(2) pg183-198 PubMed Id 32305041 First Author Ishihara, J Title Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Citation Nature Communications; 9(1) pg2163 PubMed Id 29867149 First Author Severin, I C Title Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans. Citation The Journal of Biological Chemistry; 285(23) pg17713-24 PubMed Id 20363748
