Recombinant Murine IL-5 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 215-15 Descripcion IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant Murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains. Source: E.coli Synonyms: EDF, BCDFII, TRF AA Sequence: MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg. Calculated Molecular Weight: 26.2 kDa Accession Number: P04401 Gene ID: 16191 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Immune System Inflammation Wound Healing Allergy product.subtitle.recentcitations Primer autor Wigton, E J Titulo MicroRNA-directed pathway discovery elucidates an miR-221/222-mediated regulatory circuit in class switch recombination. Citar The Journal of Experimental Medicine; 218(11) PudMed id 34586363 Primer autor Onodera, T Titulo A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site. Citar Immunity; 54(10) pg2385-2398.e10 PudMed id 34508662 Primer autor Patial, S Titulo Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs. Citar Scientific Reports; 11(1) pg15465 PudMed id 34326406