Recombinant Murine KC (CXCL1) 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 250-11 Descripcion All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2. Source: E.coli Synonyms: MGSAα, CXCL1, NAP-3, GRO1, GRO/MGSA (human), CINC (rat) AA Sequence: APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P12850 Gene ID: 14825 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. crossreactivity: Human, Mouse, Mouse + Bacteria, Rat References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing product.subtitle.recentcitations Primer autor Chang, C W Titulo Gα13 Mediates Transendothelial Migration of Neutrophils by Promoting Integrin-Dependent Motility without Affecting Directionality. Citar Journal of immunology (Baltimore, Md. : 1950); 207(12) pg3038-3049 PudMed id 34799423 Primer autor Yoon, Y Titulo Activation of the adipocyte CREB/CRTC pathway in obesity. Citar Communications Biology; 4(1) pg1214 PudMed id 34686752 Primer autor Lindzen, M Titulo Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53 Citar Oncogene; 40(21) pg3665-3679 PudMed id 33941851
