Recombinant Murine KC (CXCL1) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-11 Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2. Source: E.coli Synonyms: MGSAα, CXCL1, NAP-3, GRO1, GRO/MGSA (human), CINC (rat) AA Sequence: APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P12850 Gene ID: 14825 Note: 1mg will be provided as 2x500μg. crossreactivity: Human, Mouse, Mouse + Bacteria, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing product.subtitle.recentcitations First Author Frommhold, D Title Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. Citation The Journal of Experimental Medicine; 205(6) pg1435-46 PubMed Id 18519646 First Author Taylor, A Title SRF is required for neutrophil migration in response to inflammation. Citation Blood; 123(19) pg3027-36 PubMed Id 24574460 First Author Tager, A M Title BLTR mediates leukotriene B(4)-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis. Citation The Journal of Experimental Medicine; 192(3) pg439-46 PubMed Id 10934232
